Results 151 to 160 of about 12,144 (214)

Cyanobacteriochrome-based photoswitchable adenylyl cyclases (cPACs) for broad spectrum light regulation of cAMP levels in cells. [PDF]

J Biol Chem, 2018
Blain-Hartung M, Rockwell NC, Moreno MV, Martin SS, Gan F, Bryant DA, Lagarias JC.   +6 more
europepmc   +1 more source

Soluble adenylyl cyclase

, 2018
\(\bf Aims\) In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is poorly understood. Here we investigate whether
Schirmer, Ilona, Bualeong, Tippaporn (Dr. rer. nat.), Budde, Heidi (M. Sc.), Cimiotti, Diana (Dr. rer. nat.), Appukuttan, Avinash (Dr. rer. nat.), Klein, Nicole (M. Sc.), Steinwascher, Philip (M.Sc.), Reusch, Hans-Peter (Dr. med.), Mügge, Andreas (Prof. Dr. med.), Meyer, Rainer (Apl. Prof. Dr. rer. nat.), Ladilov, Yuri, Jaquet, Kornelia (Prof. Dr. rer. nat.)   +11 more
openaire   +1 more source

Optimization of a 1,3,4-oxadiazole series for inhibition of Ca²⁺/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain. [PDF]

Eur J Med Chem, 2019
Kaur J, Soto-Velasquez M, Ding Z, Ghanbarpour A, Lill MA, van Rijn RM, Watts VJ, Flaherty DP.   +7 more
europepmc   +1 more source

Glucagon-Like Peptide-1 Receptor Agonist and Glucagon Increase Glucose-Stimulated Insulin Secretion in Beta Cells via Distinct Adenylyl Cyclases. [PDF]

Int J Med Sci, 2018
Lee YS, Jun HS.
europepmc   +1 more source

Hypoxia induces cancer-associated cAMP/PKA signalling through HIF-mediated transcriptional control of adenylyl cyclases VI and VII. [PDF]

Sci Rep, 2017
Simko V, Iuliano F, Sevcikova A, Labudova M, Barathova M, Radvak P, Pastorekova S, Pastorek J, Csaderova L.   +8 more
europepmc   +1 more source

Pharmacological distinction between soluble and transmembrane adenylyl cyclases. [PDF]

J Pharmacol Exp Ther, 2013
Bitterman JL, Ramos-Espiritu L, Diaz A, Levin LR, Buck J.   +4 more
europepmc   +1 more source

International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. [PDF]

Pharmacol Rev, 2017
Dessauer CW, Watts VJ, Ostrom RS, Conti M, Dove S, Seifert R.   +5 more
europepmc   +1 more source

Distinct roles of soluble and transmembrane adenylyl cyclases in the regulation of flagellar motility in Ciona sperm. [PDF]

Int J Mol Sci, 2014
Shiba K, Inaba K.
europepmc   +1 more source

Olfactory adenylyl cyclase

Journal of Biological Chemistry, 1989
E Pfeuffer, S Mollner, D Lancet, T Pfeuffer   +3 more
openaire   +1 more source

"Cyclic nucleotides in plants: from obscure messengers to central regulators". [PDF]

Front Plant Sci
Świeżawska-Boniecka B, Szmidt-Jaworska A.   +1 more
europepmc   +1 more source