Localization of mRNAs Encoding Ca2+-inhibitable Adenylyl Cyclases along the Renal Tubule
Expression of Ca2+-inhibitable types V and VI adenylyl cyclases was studied by reverse transcription-polymerase chain reaction in rat renal glomeruli and nephron segments isolated by microdissection.
D. Chabardès+6 more
semanticscholar +1 more source
Gαq signalling from endosomes: A new conundrum
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley +1 more source
Intestinal brush border membranes contain regulatory subunits of adenylyl cyclase. [PDF]
Pedro Domı́nguez+3 more
openalex +1 more source
G protein‐coupled receptor‐mediated autophagy in health and disease
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan+2 more
wiley +1 more source
PGE1 and hCG Responsive Adenylyl Cyclases in Interstitial Cells from Rat Testis: Biphasic Effects of Calcium [PDF]
Jan O. Gordeladze+3 more
openalex +1 more source
Differential G protein activation by the long and short isoforms of the dopamine D2 receptor
Background and Purpose The dopamine D2 receptor is expressed as a short (D2S) and a long (D2L) isoform with 29 additional amino acids in the third intracellular loop. The D2S isoform shows higher presynaptic expression than the D2L isoform, and decreased D2S expression has recently been linked to an increased risk for schizophrenia.
David Reiner‐Link+4 more
wiley +1 more source
Optogenetic modulation of real-time nanoscale dynamics of HCN channels using photoactivated adenylyl cyclases. [PDF]
Tanwar M, Kateriya S, Nair D, Jose M.
europepmc +1 more source
Effect of Estradiol Withdrawal on Luteal Hormone-Responsive Adenylyl Cyclase and Luteal Function in the Pseudopregnant Rabbit1 [PDF]
Sharon L. Day+3 more
openalex +1 more source
Allosterism in the adenosine A2A and cannabinoid CB2 heteromer
Abstract Background and Purpose Allosterism is a regulatory mechanism for GPCRs that can be attained by ligand‐binding or protein–protein interactions with another GPCR. We have studied the influence of the dimer interface on the allosteric properties of the A2A receptor and CB2 receptor heteromer.
Claudia Llinas del Torrent+7 more
wiley +1 more source
Analysis of diverse signal transduction pathways using the genetic model system Caenorhabditis elegans [PDF]
Signal transduction allows cells to respond to signals from their environment and is therefore important for most biological processes. The binding of an extracellular signalling molecule to a cell-surface receptor is the first step in most signal ...
Moorman, Celine
core