Results 171 to 180 of about 16,663 (278)

Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of neuropathic and inflammatory pain in adult female mice [PDF]

, 2021
Zhaoxiang Zhou, Wantong Shi, Kexin Fan, Man Xue, Si-Bo Zhou, Qi‐Yu Chen, Jing-Shan Lu, Xu‐Hui Li, Min Zhuo   +8 more
openalex   +1 more source

Regulation of IKs Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase [PDF]

, 2019
Yong Li, Thomas Hof, Tanya A. Baldwin, Lei Chen, Robert S. Kass, Carmen Dessauer   +5 more
openalex   +1 more source

Nicotiflorin Alleviates Obesity by Activating Brown Adipose Tissue Through the β3–Adrenergic Receptor Pathway

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Objective This study investigated the antiobesity effects of nicotiflorin, a flavonol glycoside structurally related to rutin, by examining its ability to activate brown adipose tissue (BAT) through the β3–adrenergic receptor (β3‐AR) pathway in mice with high‐fat diet (HFD)–induced obesity.
Chun-Yen Chiu, Chung-Yuh Tzeng, Shin-Wu Liu, Chun-Jung Chen, Yu-Hsiang Kuan, Chung-Chi Hu, Wen-Ying Chen, Kim Wei Chan   +7 more
wiley   +1 more source

Soluble adenylyl cyclase

, 2018
\(\bf Aims\) In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is poorly understood. Here we investigate whether
Schirmer, Ilona, Bualeong, Tippaporn (Dr. rer. nat.), Budde, Heidi (M. Sc.), Cimiotti, Diana (Dr. rer. nat.), Appukuttan, Avinash (Dr. rer. nat.), Klein, Nicole (M. Sc.), Steinwascher, Philip (M.Sc.), Reusch, Hans-Peter (Dr. med.), Mügge, Andreas (Prof. Dr. med.), Meyer, Rainer (Apl. Prof. Dr. rer. nat.), Ladilov, Yuri, Jaquet, Kornelia (Prof. Dr. rer. nat.)   +11 more
openaire   +1 more source

Modulation of G-protein expression and adenylyl cyclase signaling by high glucose in vascular smooth muscle*1 [PDF]

, 2004
Shahrir Hashim
openalex   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira, Robson Xavier Faria, Wei Wang   +2 more
wiley   +1 more source

Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases. [PDF]

Cell Chem Biol, 2019
O'Banion CP, Vickerman BM, Haar L, Lawrence DS.   +3 more
europepmc   +1 more source

IP₃-mediated Ca²⁺ release regulates atrial Ca²⁺ transients and pacemaker function by stimulation of adenylyl cyclases.

Am J Physiol Heart Circ Physiol, 2021
Capel RA, Bose SJ, Collins TP, Rajasundaram S, Ayagama T, Zaccolo M, Burton RB, Terrar DA.   +7 more
europepmc   +1 more source

Effects of selective γ3-adrenoceptor agonist ICI 215001 on adenylyl cyclase system and distribution of γ3-adrenoceptors in various tissues of rats.

, 1993
Yasuto Ohsaka, Yukiko Tokumitsu, Toshihide Yoshida, Yasuyuki Nomura   +3 more
openalex   +1 more source

Effects of hypothyroidism on brown adipose tissue adenylyl cyclase activity [PDF]

, 1996
Suzy D. Carvalho
openalex   +1 more source