Endothelial Adherens Junctions [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2000 The principle of the molecular organization of adherens junctions follows a uniform pattern, which is found in epithelial, muscular, neuroneal as well as in endothelial cells and is highly conserved among species. Transmembrane molecules of the cadherin family link to catenins, which anchor the adhesion plaque to the cytoskeleton.
Petzelbauer, Peter +2 more
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FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. [PDF]
PLoS ONE, 2013 Proper development and tissue maintenance requires cell-cell adhesion structures, which serve diverse and crucial roles in tissue morphogenesis. Epithelial tissues have three main types of cell-cell junctions: tight junctions, which play a major role in ...
Henry P Foote +2 more
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'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells: modulation of the adherens junction complex by ketamine [PDF]
, 2013 Ketamine, a mild hallucinogenic class C drug, is the fastest growing ‘party drug’ used by 16–24 year olds in the UK. As the recreational use of Ketamine increases we are beginning to see the signs of major renal and bladder complications. To date however,
A Masszi +33 more
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Loss of E-cadherin is causal to pathologic changes in chronic lung disease
Communications Biology, 2022 Specific loss of the adherens junction protein E-cadherin in alveolar epithelial and airway ciliated cells causes chronic lung disease.
Baishakhi Ghosh +21 more
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Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies [PDF]
, 1992 We examined the roles of the extracellular domains of a gap junction protein and a cell adhesion molecule in gap junction and adherens junction formation by altering cell interactions with antibody Fab fragments.
Johnson, Ross G. +3 more
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Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion. [PDF]
PLoS ONE, 2013 Flotillin-1 and flotillin-2 are two homologous, membrane raft associated proteins. Although it has been reported that flotillins are involved in cell adhesion processes and play a role during breast cancer progression, thus making them interesting future
Nina Kurrle +5 more
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Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength [PDF]
, 2002 By tethering intermediate filaments (IFs) to sites of intercellular adhesion, desmosomes facilitate formation of a supercellular scaffold that imparts mechanical strength to a tissue.
Amargo, Evangeline V. +11 more
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Interplay between tight junctions & adherens junctions [PDF]
Experimental Cell Research, 2017 Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell contact are the adherens junctions and tight junctions. The adherens junctions mediate cell-cell adhesion via the actions of nectins and cadherins.
Hannah K, Campbell +2 more
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Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2. [PDF]
PLoS ONE, 2012 The fibroblast growth factor (FGF) system plays a critical role in the maintenance of vascular integrity via enhancing the stability of VE-cadherin at adherens junctions. However, the precise molecular mechanism is not well understood.
Kunihiko Hatanaka +3 more
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