Results 81 to 90 of about 52,241 (196)

Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex [PDF]

, 2019
Epithelial monolayers are one-cell thick tissue sheets that separate internal and external environments. As part of their function, they have to withstand extrinsic mechanical stresses applied at high strain rates.
,, Asadipour, N, Barrientos, R, Baum, B, Bonfanti, A, Charras, G, Duda, M, Fouchard, J, Fujita, Y, Harris, A, Kabla, A, Khalilgharibi, N, Mao, Y, Miodownik, M, Mosaffa, P, Muñoz, JJ, Yonis, A   +16 more
core   +4 more sources

Formin' adherens junctions

The Journal of Cell Biology, 2003
Epithelial cells zipper together thanks to linear actin cables—cables that assemble at newly formed adherens junctions to stabilize them, thereby counteracting retractive forces at sites of cell–cell contact. Now, Agnieszka Kobielak, Amalia Pasolli, and Elaine Fuchs (Rockefeller University, New York, NY) have found that formin-1 drives the actin ...
openaire   +2 more sources

Restraint Stress Induced Hyperpermeability and Damage of the Blood-Brain Barrier in the Amygdala of Adult Rats

Frontiers in Molecular Neuroscience, 2019
Intense or prolonged exposure to stress can damage various brain structures, including the amygdala and hippocampus, which are associated with emotional-cognitive functions. Furthermore, this deterioration has been linked to a myriad of neurodegenerative
Guangming Xu, Yingmin Li, Chunling Ma, Chuan Wang, Zhaoling Sun, Yiwen Shen, Li Liu, Shujin Li, Xiaojing Zhang, Bin Cong   +9 more
doaj   +1 more source

DHT deficiency perturbs the integrity of the rat seminiferous epithelium by disrupting tight and adherens junctions

Folia Histochemica et Cytobiologica, 2011
In rats with a DHT deficiency induced by finasteride, morphological changes in the seminiferous epithelium were observed. The structural alterations were manifested by the premature germ cells sloughing into the lumen of seminiferous tubules.
Barbara Wiszniewska, Lidia Wenda-Różewicka, Mariola Marchlewicz, Agnieszka Kolasa   +3 more
doaj   +1 more source

Adherens Junctions: Demonstration in Human Epidermis

Journal of Investigative Dermatology, 1993
Adherens junctions are intercellular and cell-matrix junctions that, like desmosomes and hemidesmosomes, mediate adhesion of cells to each other or to matrix structures. These junctions have been detected recently in cultured human keratinocytes, indicating that they may be of importance in epidermis.
Kaiser, Hans W., Ness, Winfried, Jungblut, Isabel, Briggaman, Robert A., Kreysel, Hans W., O'Keefe, Edward J.   +5 more
openaire   +3 more sources

WIF1 prevents Wnt5A mediated LIMK/CFL phosphorylation and adherens junction disruption in human vascular endothelial cells

Journal of Inflammation, 2017
Background Wnt5A is released by activated macrophages and elevated levels have been detected in sepsis patients with severe systemic inflammation. However, the signalling and functional effects of Wnt5A in the vascular endothelial cells (VEC) remained ...
Tom Skaria, Esther Bachli, Gabriele Schoedon   +2 more
doaj   +1 more source

Correction to: Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation

Cardiovascular Diabetology, 2017
This article was unintentionally published twice in this journal, by the same authors. The following should be considered the version of record and used for citation purposes: “Mehran Haidari, Wei Zhang, James T Willerson and Richard AF Dixon, Disruption
Mehran Haidari, Wei Zhang, James T. Willerson, Richard A. F. Dixon   +3 more
doaj   +1 more source

Force transduction by cadherin adhesions in morphogenesis [version 1; peer review: 3 approved]

F1000Research, 2019
Mechanical forces drive the remodeling of tissues during morphogenesis. This relies on the transmission of forces between cells by cadherin-based adherens junctions, which couple the force-generating actomyosin cytoskeletons of neighboring cells ...
Willem-Jan Pannekoek, Johan de Rooij, Martijn Gloerich   +2 more
doaj   +1 more source

Molecular components of the adherens junction

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2008
Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins.
Niessen, Carien M., Gottardi, Cara J.
openaire   +2 more sources

Role of airway epithelial barrier dysfunction in pathogenesis of asthma

Allergology International, 2018
Bronchial asthma is characterized by persistent cough, increased sputum, and repeated wheezing. The pathophysiology underlying these symptoms is the hyper-responsiveness of the airway along with chronic airway inflammation.
Yasuhiro Gon, Shu Hashimoto
doaj   +1 more source