Results 31 to 40 of about 14,945 (190)

Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli

Biology, 2013
Fimbriae are long, proteinaceous adhesion organelles expressed on the bacterial envelope, evolutionarily adapted by Escherichia coli strains for the colonization of epithelial linings. Using glycan arrays of the Consortium for Functional Glycomics (CFG),
Manfred Wuhrer, Julie Bouckaert, Stefan Oscarson, André M. Deelder, Yann Guérardel, Emeline Fabre, Johan D. M. Olsson, Manfred S. Weiss, Lieven Buts, Arjen R. de Boer, Emanuela Lonardi, Kristof Moonens   +11 more
doaj   +1 more source

MecVax supplemented with CFA MEFA-II induces functional antibodies against 12 adhesins (CFA/I, CS1–CS7, CS12, CS14, CS17, and CS21) and 2 toxins (STa, LT) of enterotoxigenic Escherichia coli (ETEC)

Microbiology Spectrum
Enterotoxigenic Escherichia coli (ETEC) strains that produce various adhesins and one or two enterotoxins are the leading causes of children’s diarrhea and travelers’ diarrhea.
Chongyang Zhang, Siqi Li, Ipshita Upadhyay, Kathyrn L. Lauder, David A. Sack, Weiping Zhang   +5 more
doaj   +1 more source

Crystal Structure and Mutational Analysis of the DaaE Adhesin of Escherichia coli [PDF]

Journal of Biological Chemistry, 2006
DaaE is a member of the Dr adhesin family of Escherichia coli, members of which are associated with diarrhea and urinary tract infections. A receptor for Dr adhesins is the cell surface protein, decay-accelerating factor (DAF). We have carried out a functional analysis of Dr adhesins, as well as mutagenesis and crystallographic studies of DaaE, to ...
Natalia, Korotkova, Isolde, Le Trong, Ram, Samudrala, Konstantin, Korotkov, Cristina P, Van Loy, Anh-Linh, Bui, Steve L, Moseley, Ronald E, Stenkamp   +7 more
openaire   +2 more sources

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Adhesins and invasins of pathogenic Escherichia coli

International Journal of Medical Microbiology, 2005
Pathogenic E. coli cause both intestinal and extra-intestinal infections in humans and animals. Bacteria must be able to adhere to host cells if they are to colonize and to invade their hosts. Numerous E. coli adhesins with different morphological features and receptor specificities have been identified.
openaire   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Prevalence of Genes Encoding Outer Membrane Virulence Factors Among Fecal Escherichia coli Isolates [PDF]

International Journal of Basic Science in Medicine, 2017
Objective: Escherichia coli is commensal bacterium of human intestine. The gut is a common pool of E. coli isolates causing urinary tract infections (UTIs). Some of fecal E.
Ahmad Rashki, Hossain Ali Abdi, Milad Shookohi   +2 more
doaj   +1 more source

Recent Genetic Changes Affecting Enterohemorrhagic Escherichia coli Causing Recurrent Outbreaks

Microbiology Spectrum, 2022
Enterohemorrhagic E. coli (EHEC) is responsible for significant human illness, death, and economic loss. The main reservoir for EHEC is cattle, but plant-based foods are common vectors for human infection.
Joshua L. Cherry
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Molecular structure of adhesin domains in Escherichia coli fimbriae

International Journal of Medical Microbiology, 2005
Crystal structures of FimH, PapG, GafD, and DraE fimbrial adhesin subunits or lectin domains have been resolved. These adhesins bind to different targets and are only distantly related in amino acid sequence. The overall structures of the fimbrial lectins, however, appear similar, suggesting that the fimbrial lectins have diverged from a common ...
Benita, Westerlund-Wikström, Timo K, Korhonen   +1 more
openaire   +2 more sources