Results 31 to 40 of about 26,689 (231)

Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins

mBio, 2016
The first step in the infection of humans by microbial pathogens is their adherence to host tissue cells, which is frequently based on the binding of carbohydrate-binding proteins (lectin-like adhesins) to human cell receptors that expose glycans.
Francesco S. Ielasi, Mitchel Alioscha-Perez, Dagmara Donohue, Sandra Claes, Hichem Sahli, Dominique Schols, Ronnie G. Willaert   +6 more
doaj   +1 more source

Fimbrial Adhesins Produced by Atypical Enteropathogenic Escherichia coli Strains [PDF]

Applied and Environmental Microbiology, 2011
ABSTRACT Atypical enteropathogenic Escherichia coli (aEPEC) has emerged as a significant cause of pediatric diarrhea worldwide; however, information regarding its adherence mechanisms to the human gut mucosa is lacking. In this study, we investigated the prevalence of several ( fimA
Hernandes, Rodrigo T. UNIFESP, Velsko, Irina, Sampaio, Suely C. F. UNIFESP, Elias Junior, Waldir Pereira UNIFESP, Robins-Browne, Roy M., Gomes, Tania A. T. UNIFESP, Giron, Jorge A.   +6 more
openaire   +3 more sources

Infections with Avian Pathogenic and Fecal Escherichia coli Strains Display Similar Lung Histopathology and Macrophage Apoptosis [PDF]

, 2012
The purpose of this study was to compare histopathological changes in the lungs of chickens infected with avian pathogenic (APEC) and avian fecal (Afecal) Escherichia coli strains, and to analyze how the interaction of the bacteria with avian ...
AD Kennedy, André Mendes Ribeiro Corrêa, Bernd Kaspers, C Ciraci, C Ciraci, C Ewers, CD Tyler, Christa Ewers, CM Dozois, David Driemeier, E-M Antão, E-M Antão, F de Pace, Fabiana Horn, G Li, GW Li, H Beug, H He, I Chouikha, J Dai, J Mast, JN Maina, Karl Dietrich Weyrauch, LB Matter, Lothar H. Wieler, M Bastiani, M Caza, M Dho, M Dho-Moulin, M Mellata, Markus M. Heimesaat, MC Vidotto, Nicolle Lima Barbieri, P Germon, RM Dwars, S Reese, SA Pourbakhsh, SA Pourbakhsh, Susanne Glodde, TJ Johnson, Y Gavrieli   +40 more
core   +7 more sources

Adhesins as Targets for Vaccine Development

Emerging Infectious Diseases, 1999
Blocking the primary stages of infection, namely bacterial attachment to host cell receptors and colonization of the mucosal surface, may be the most effective strategy to prevent bacterial infections. Bacterial attachment usually involves an interaction
Theresa M. Wizemann, John E. Adamou, Solomon Langermann   +2 more
doaj   +1 more source

Autotransporter Adhesins in Escherichia coli Pathogenesis

PROTEOMICS, 2017
AbstractMost bacteria produce adhesion molecules to facilitate the interaction with host cells and establish successful infections. An important group of bacterial adhesins belong to the autotransporter (AT) superfamily, the largest group of secreted and outer membrane proteins in Gram‐negative bacteria.
Julieanne L, Vo, Gabriela Constanza, Martínez Ortiz, Pramod, Subedi, Shivakumar, Keerthikumar, Suresh, Mathivanan, Jason J, Paxman, Begoña, Heras   +6 more
openaire   +3 more sources

Whatever makes them stick – Adhesins of avian pathogenic Escherichia coli

Veterinary Microbiology, 2021
Avian pathogenic Escherichia coli (APEC) is associated with extraintestinal infections and the development of colibacillosis, causing high mortality in farm birds and extensive losses in the poultry industry worldwide. The virulence of APEC is a complex phenomenon associated with numerous mechanisms involving a variety of extracellular and ...
Adrianna Aleksandrowicz, Muhammad Moman Khan, Katarzyna Sidorczuk, Mateusz Noszka, Rafał Kolenda   +4 more
openaire   +2 more sources

The structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket [PDF]

, 2012
P pili are hairlike polymeric structures that mediate binding of uropathogenic Escherichia coli to the surface of the kidney via the PapG adhesin at their tips.
Baga M, Bann JG, Barnhart MM, Dodson KW, Dodson KW, Doublie S, Gong M, Griebling TL, Henderson NS, Hess B, Holmgren A, Hooton TM, Hultgren SJ, Hung DL, Hung DL, Hung DL, Jacob-Dubuisson F, Jones CH, Justice SS, Kabsch W, Knight SD, Kuehn MJ, Kuehn MJ, Leslie A, Martinez JJ, Munera D, Nishiyama M, Painter J, Pellecchia M, Phan G, Remaut H, Remaut H, Roberts JA, Roberts JA, Rose RJ, Sauer FG, Sauer FG, Sauer FG, Saulino ET, Saulino ET, Sheldrick GM, Slonim LN, Striker R, Stromberg N, Verger D, Verger D, Volkan E, Wright KJ, Zavialov AV   +48 more
core   +2 more sources

Detection of cytotoxic necrotizing factor types 1 and 2 among fecal Escherichia coli isolates from brazilian children with and without diarrhea

Memorias do Instituto Oswaldo Cruz, 2004
The enteropathogenic role of cytotoxic necrotizing factor (CNF)-producing Escherichia coli was investigated by searching cnf genes among 2074 isolates from 200 children with and 200 without acute diarrhea in Brazil.
Ana Terezinha Tavechio, Lilian Regina M Marques, Cecília Mari Abe, Tânia AT Gomes   +3 more
doaj   +1 more source

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection [PDF]

, 2018
Significance The emergence of multidrug-resistant bacteria, including uropathogenic Escherichia coli (UPEC), makes the development of targeted antivirulence therapeutics a critical focus of research.
Chugani, Ryan, Conover, Matt S., Hibbing, Michael E., Hultgren, Scott J., Janetka, James W., Kalas, Vasilios, Maddirala, Amarendar Reddy, Mydock-McGrane, Laurel K., Pinkner, Jerome S.   +8 more
core   +2 more sources

Lactobacillus reuteri inhibition of Enteropathogenic Escherichia coli adherence to human intestinal epithelium [PDF]

, 2016
Enteropathogenic Escherichia coli (EPEC) is a major cause of diarrheal infant death in developing countries, and probiotic bacteria have been shown to provide health benefits in gastrointestinal infections.
Bartman, Bernet, Bray, Casas, De Keersmaecker, Etzold, Etzold, Etzold, Forestier, Frese, Havenaar, Jensen, Johansson, Juge, Kim, Knutton, Lanata, Lebeer, Levine, MacKenzie, Miyoshi, Moon, Nataro, Navabi, Ogawa, Oh, Ouwehand, Roos, Savino, Sazawal, Schüller, Servin, Sheng, Sherman, Shornikova, Shornikova, Szajewska, Talarico, Tuomola, Valeur, van Klinken, Viswanathan, Wong   +42 more
core   +2 more sources