Results 101 to 110 of about 1,904,554 (255)
Identification and analysis of "Plasmodium falciparum" genes mediating cytoadherence [PDF]
, 1999 Malaria is the most important parasitic disease of man: almost two billion people live in areas in which the most pathogenic human Plasmodium species is transmitted. The parasite P.
Degen, Roland
core +1 more source
Memorias do Instituto Oswaldo Cruz, 1998 Infection of a susceptible host with the blood fluke Schistosoma mansoni results in the formation of periovular granulomas and subsequent fibrosis in the target organs.
Werner Jacobs, Eric Van Marck
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice [PDF]
, 2013 Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury.
Imhof, Beat A. +24 more
core +2 more sources
Leukocyte adhesion - a fundamental process in leukocyte physiology
Brazilian Journal of Medical and Biological Research, 1999 Leukocyte adhesion is of pivotal functional importance. The adhesion involves several different adhesion molecules, the most important of which are the leukocyte ß2-integrins (CD11/CD18), the intercellular adhesion molecules, and the selectins.
Gahmberg C.G. +7 more
doaj
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Osteoprotegerin and adhesion molecules
, 2010 The glycoprotein osteoprotegerin (OPG) plays an important role in controlling normal bone remodelling by inhibiting osteoclast function. More recently, OPG has been implicated in a number of diseases associated with inflammation.
Jonathan Golledge +3 more
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Adhesion molecules in renal disease [PDF]
, 1995 Adhesion molecules are a heterogeneous class of ligands/receptors that mediate cell adhesion, either to other cells or to the extracellular matrix. Cell adhesion is of fundamental importance to an impressive number of physiological and pathological ...
Dal Canton, Antonio
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source