Results 51 to 60 of about 1,904,554 (255)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

THE STUDY OF SOLUBLE ADHESION MOL¬ECULES (SICAM-1, SVCAM-1, SELAM-1) IN SE¬RUM AND MEMBRANE FORM OF ADHESION MOLECULES (VCAM-1, ICAM-1) ON THE MONO¬CYTES IN DIABETIC SUBJECTS TYPE 1

Iranian Journal of Allergy, Asthma and Immunology, 2000
The adhesion molecules are involved in adhesion of leukocytes to endothelial cells and other immune cells. Not only adhesion molecules have membrane form, but they also have soluble form.
K. Bahman Sufiani, Sh. Shar Gasimpour, A.R. Salek Mogaddam,   K. Entezami, A. Rajab   +4 more
doaj  

Cadherin Cell Adhesion System in Canine Mammary Cancer: A Review

Veterinary Medicine International, 2012
Cadherin-catenin adhesion complexes play important roles by providing cell-cell adhesion and communication in different organ systems. Abnormal expression of cadherin adhesion molecules constitutes a common phenomenon in canine mammary cancer and has ...
Adelina Gama, Fernando Schmitt
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The importance of selected cell adhesion molecules in thyroid cancer

Journal of Education, Health and Sport, 2018
Thyroid cancer is the most common malignant tumour of the endocrine system. It accounts for ca. 2% of all malignant tumours in the world, ranking it 16th in the overall classification. Its most common histology type is the papillary carcinoma originating
Magdalena Urbańczuk, Marcin Urbańczuk, Tomasz Tuzim, Katarzyna Schab, Kamila Bąk, Marcin Lewicki   +5 more
doaj   +3 more sources

15-Deoxy-Delta12,14-prostaglandin J2 modifies components of the proteasome and inhibits inflammatory responses in human endothelial cells

Frontiers in Immunology, 2016
15-Deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) is an electrophilic lipid mediator derived from PGD2 with potent anti-inflammatory effects. These are likely to be due to the covalent modification of cellular proteins, via a reactive α,β-unsaturated ...
Simone Marcone, Paul Evans, Desmond J Fitzgerald   +2 more
doaj   +1 more source

Perinatal Inflammation: Could Partial Blocking of Cell Adhesion Molecule Function Be a Solution?

Children, 2021
In spite of the great advances made in recent years in prenatal and perinatal medicine, inflammation can still frequently result in injury to vital organs and often constitutes a major cause of morbidity.
Nikolaos Vrachnis, Dimitrios Zygouris, Dionysios Vrachnis, Nikolaos Roussos, Nikolaos Loukas, Nikolaos Antonakopoulos, Georgios Paltoglou, Stavroula Barbounaki, Georgios Valsamakis, Zoi Iliodromiti   +9 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Bifidobacterium bifidum Extracellular Sialidase Enhances Adhesion to the Mucosal Surface and Supports Carbohydrate Assimilation

mBio, 2017
Bifidobacterium is a natural inhabitant of the human gastrointestinal (GI) tract. We studied the role of the extracellular sialidase (SiaBb2, 835 amino acids [aa]) from Bifidobacterium bifidum ATCC 15696 in mucosal surface adhesion and carbohydrate ...
Keita Nishiyama, Yuji Yamamoto, Makoto Sugiyama, Takashi Takaki, Tadasu Urashima, Satoru Fukiya, Atsushi Yokota, Nobuhiko Okada, Takao Mukai   +8 more
doaj   +1 more source

Immunohistochemical study of adhesion molecules in irritable bowel syndrome: A comparison to inflammatory bowel diseases

Advanced Biomedical Research, 2021
Background: The surface of endothelial cells is covered with cell adhesion molecules including E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule 1 (VCAM-1) that mediate the adhesion and extravasation of ...
Antigony Mitselou, Vasileios Grammeniatis, Anna Varouktsi, Stamatis S Papadatos, Antonios Klaroudas, Konstantinos Katsanos, Vasiliki Galani   +6 more
doaj   +1 more source