Results 61 to 70 of about 839,688 (290)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor-Deficient Mice [PDF]

open access: yes, 2008
Objective—Atherosclerosis is a vascular disease that involves lesion formation at sites of disturbed flow under the influence of genetic and environmental factors.
Arora, Shikha   +9 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Evaluation of serum levels of cell adhesion molecules (ICAM-1) and vascular adhesion molecules (VCAM-1) following a resistance training program in middle-aged and elderly men with hypertension [PDF]

open access: yesمجله علوم پزشکی فیض (پیوسته)
Background and Aim: Cell adhesion molecules (ICAM-1) and vascular adhesion molecules (VCAM-1) play critical roles in endothelial function and cardiovascular diseases.
Bizhan Hooshmand Moghadam   +3 more
doaj  

15-Deoxy-Delta12,14-prostaglandin J2 modifies components of the proteasome and inhibits inflammatory responses in human endothelial cells

open access: yesFrontiers in Immunology, 2016
15-Deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) is an electrophilic lipid mediator derived from PGD2 with potent anti-inflammatory effects. These are likely to be due to the covalent modification of cellular proteins, via a reactive α,β-unsaturated ...
Simone Marcone   +2 more
doaj   +1 more source

Analysis on the relevance of asthma susceptibility with the alteration of integrin β 4 expression. [PDF]

open access: yesPLoS ONE, 2014
Accumulated research has suggested the importance of the adhesion molecules modulation as therapeutic approach for bronchial asthma. Adhesion molecules expression alteration contributes to the pathogenesis of asthma.
Yang Xiang   +7 more
doaj   +1 more source

Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α [PDF]

open access: yes, 2000
Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level.
Akimitsu T.   +11 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The importance of selected cell adhesion molecules in thyroid cancer

open access: yesJournal of Education, Health and Sport, 2018
Thyroid cancer is the most common malignant tumour of the endocrine system. It accounts for ca. 2% of all malignant tumours in the world, ranking it 16th in the overall classification. Its most common histology type is the papillary carcinoma originating
Magdalena Urbańczuk   +5 more
doaj   +3 more sources

Synaptic Cell Adhesion Molecules in Alzheimer’s Disease

open access: yesNeural Plasticity, 2016
Alzheimer’s disease (AD) is a neurodegenerative brain disorder associated with the loss of synapses between neurons in the brain. Synaptic cell adhesion molecules are cell surface glycoproteins which are expressed at the synaptic plasma membranes of ...
Iryna Leshchyns’ka, Vladimir Sytnyk
doaj   +1 more source

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