Results 101 to 110 of about 282,105 (396)

Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification

open access: yesAdipocyte, 2020
The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for quantifying adipocyte size has yet to be standardized.
Anne S Maguire   +5 more
doaj   +1 more source

Bioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity

open access: yesAdipocyte, 2022
Obesity is a complex medical condition that affects multiple organs in the body. However, the underlying mechanisms of obesity, as well as its treatment, are largely unexplored.
Yun Yu   +9 more
doaj   +1 more source

Welcome toAdipocyte [PDF]

open access: yesAdipocyte, 2012
When Ron Landes approached me last summer with the idea to launch a journal dedicated to adipose tissue research, it resonated immediately; I loved the idea. Thus, it is with great pleasure that we launch Adipocyte, the first international peer-reviewed multi-disciplinary journal to focus exclusively on research covering all aspects of adipose tissue ...
openaire   +2 more sources

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

pubCounteR: an R package for interrogating published literature for experimentally-derived gene lists within a user-defined biological context

open access: yesFrontiers in Bioinformatics
Basic and clinical biomedical research relies heavily on modern large-scale datasets that include genomics, transcriptomics, epigenomics, metabolomics, and proteomics, among other “Omics”. These research tools very often generate lists of candidate genes
Marina Leer   +11 more
doaj   +1 more source

Non-obesogenic doses of palmitate disrupt circadian metabolism in adipocytes

open access: yesAdipocyte, 2019
Saturated fatty acids, such as palmitate, lead to circadian disruption. We aimed at studying the effect of low doses of palmitate on circadian metabolism and to decipher the mechanism by which fatty acids convey their effect in adipocytes.
Yael Tal, Nava Chapnik, Oren Froy
doaj   +1 more source

Insulin-induced serine 22 phosphorylation of retinoid X receptor alpha is dispensable for adipogenesis in brown adipocytes

open access: yesAdipocyte, 2020
Insulin action initiates a series of phosphorylation events regulating cellular differentiation, growth and metabolism. We have previously discovered, in a mass spectrometry-based phosphoproteomic study, that insulin/IGF-1 signalling induces ...
Jacob Ardenkjær-Larsen   +8 more
doaj   +1 more source

Relationship between epicardial adipose tissue thickness and epicardial adipocyte size with increasing body mass index

open access: yesAdipocyte, 2019
Macroscopic deposition of epicardial adipose tissue (EAT) has been strongly associated with numerous indices of obesity and cardiovascular disease risk. In contrast, the morphology of EAT adipocytes has rarely been investigated.
Hamish M. Aitken-Buck   +14 more
semanticscholar   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Ginsenoside Rb2 improves insulin resistance by inhibiting adipocyte pyroptosis

open access: yesAdipocyte, 2020
Pyroptosis plays a critical role in the development of obesity-associated inflammation and insulin resistantance (IR). Ginsenoside Rb2 (Rb2), the main component of ginsenosides has drawn appreciable interest in the context of glucose metabolism.
Yi Lin   +6 more
doaj   +1 more source

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