Results 181 to 190 of about 181,955 (307)

Autologous Extracellular Matrix‐Based Cell‐Free Therapy for Tissue Regeneration Through Trem2+ Macrophages Mediated Angiogenesis

Exploration, EarlyView.
ADF is prepared as a cell‐free bio‐membrane from autologous adipose ECM using simple physical techniques inspired by “papermaking”. It boasts superior properties and facilitates tissue regeneration through Trem2+ macrophages‐mediated angiogenesis. ADF can be stored long‐term for personalized medicine, offering insights into autologous ECM preservation ...
Mengmeng Hou, Nini Shi, Yajie Guo, Jiezhang Tang, Han Peng, Baoyan Liang, Yixuan Yu, Chenggang Yi, Huichen Li   +8 more
wiley   +1 more source

HIF1α reinforces PPARγ-dependent metabolic rechanneling to support lipid accumulation in adipocytes. [PDF]

Front Mol Med
Zhu C, Wu M, Pham MD, Wang Y, Das AP, Mao Y, Mirtschink P, Yuan T, Krishnan J.   +8 more
europepmc   +1 more source

EVI1 mediated stimulation of 3T3-L1 preadipocyte differentiation is CtBP dependent [PDF]

, 2017
Al-Hasan, M., Bartholomew, C., Craft, J.A., Graham, A., Ireland, M. J.   +4 more
core   +1 more source

Rumen Mycobiome Thiamine Metabolism Contributes to Subacute Rumen Acidosis Tolerance in Goats Through Enhancing Epithelial Cell Proliferation via IGFBP2/IGF1 Axis Activation

Exploration, EarlyView.
Schematic illustration of the mechanism underlying the differences between SARA‐susceptible and SARA‐tolerant dairy goats fed a high‐concentrate diet. SARA‐susceptible goats (HCS) exhibit low rumen pH and metabolic decline, characterized by epithelial inflammation.
Jingyi Xu, Xiaodong Chen, Yi Ma, Jianrong Ren, Guanghao Xu, Peilin Zhang, Wenhao Jia, Quanqiu Deng, Yuquan Xiao, Junhu Yao, Shengru Wu   +10 more
wiley   +1 more source

Hypoxia-inducible factor 1αa regulates lipid metabolism to coordinate adipocyte hypertrophy and hyperplasia in grass carp. [PDF]

J Biol Chem
Wei M, Tian Z, Song L, Xue R, Li H, Ji H, Sun J.   +6 more
europepmc   +1 more source

Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism

Food Bioengineering, EarlyView.
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing, Shanshan Deng, Mengyao Zhao, Liming Zhao   +3 more
wiley   +1 more source

Serum Response Factor (SRF) promotes actin cytoskeletal organization in adipocytes to support adaptive hypertrophic expansion and tissue remodeling during obesity in mice. [PDF]

Metabolism
So J, Wann J, Kim K, Taleb S, Kim HG, Kumari M, Banks AS, Dong XC, Roh HC.   +8 more
europepmc   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Nuclear Myosin 1 links genomic architecture to adipose tissue remodeling, metabolic inflammation and obesity in mice. [PDF]

Cell Death Dis
Khalaji S, Venit T, Lukáčová Z, Fambri V, Shrestha R, Kaluarachchi S, Boitet M, Fagny M, Saldi G, Percipalle P.   +9 more
europepmc   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source