Results 41 to 50 of about 183,197 (307)
Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells. [PDF]
, 2014 The increased incidence of obesity and metabolic disease underscores the importance of elucidating the biology of adipose tissue development. The recent discovery of cell surface markers for prospective identification of adipose precursor cells (APCs) in
Costa, Maria José +3 more
core +2 more sources
Cell Metabolism, 2010 We are pleased to present in this issue of Cell Metabolism a review series on brown adipocytes. Until recently, brown adipose tissue (BAT) was principally studied by a handful of investigators focused on rodents and newborn mammals, and, at times, their work was deemed more an exercise in scientific curiosity than an issue relevant to human health.
Emambokus, Nikla, Wang, Charlotte
openaire +2 more sources
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
γ-synuclein is a novel player in the control of body lipid metabolism [PDF]
, 2013 Peer reviewedPublisher ...
Buchman, Vladimir L +3 more
core +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Insulin prevents fatty acid induced increase of adipocyte size
Adipocyte, 2022 Metabolic disorders related to obesity are largely dependent on adipose tissue hypertrophy, which involves adipocyte hypertrophy and increased adipogenesis.
Emmanuelle Berger, Alain Géloën
doaj +1 more source
Fighting obesity by targeting factors regulating beige adipocytes. [PDF]
, 2018 Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K +2 more
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FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Nature Communications, 2017 Despite being an important cancer drug target, the role of epigenetic reader Brd4 in cell differentiation and development remains unclear. Here, the authors provide evidence that Brd4 plays an important role in adipogenesis and myogenesis by binding to ...
Ji-Eun Lee +9 more
doaj +1 more source
Triacylglycerol synthesis in rat adipose tissue : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1983 Adipose tissue consists of two types of cell; the adipocyte and the non-adipocyte {Rodbell, 1964). The adipocyte is unique amongst mammalian cell types in that one class of component {TG) comprises up to 80% of its weight.
Wilson, Russell Douglas
core