Results 51 to 60 of about 106,595 (265)

Integrative analyses of biomarkers and pathways for adipose tissue after bariatric surgery

Adipocyte, 2020
We explored potential biomarkers and molecular mechanisms regarding multiple benefits after bariatric surgery. Differentially expressed genes (DEGs) for subcutaneous adipose tissue (AT) after bariatric surgery were identified by analyzing two expression ...
Yingshan Liu, Jing Jin, Yanshan Chen, Chuna Chen, Zhenguo Chen, Lingling Xu   +5 more
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Ubiquitin ligase RNF20 coordinates sequential adipose thermogenesis with brown and beige fat-specific substrates

Nature Communications
In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli.
Yong Geun Jeon, Hahn Nahmgoong, Jiyoung Oh, Dabin Lee, Dong Wook Kim, Jane Eunsoo Kim, Ye Young Kim, Yul Ji, Ji Seul Han, Sung Min Kim, Jee Hyung Sohn, Won Taek Lee, Sun Won Kim, Jeu Park, Jin Young Huh, Kyuri Jo, Je-Yoel Cho, Jiyoung Park, Jae Bum Kim   +18 more
doaj   +1 more source

In vitro transdifferentiation of human adipose tissue-derived stem cells to neural lineage cells - a stage-specific incidence

Adipocyte, 2019
The present Study investigated the intrinsic ability of adipose tissue-derived stem cells (ADSCs) and their neural transdifferentiation in a stage-specific manner.
Subathra Radhakrishnan, Omana Anna Trentz, Mettu Srinivas Reddy, Mohamed Rela, Mahesh Kandasamy, Shanmugaapriya Sellathamby   +5 more
doaj   +1 more source

Adipocyte ADAM17 plays a limited role in metabolic inflammation

Adipocyte, 2020
The role of ADAM17, its substrates, and its natural inhibitor has been well studied in the context of inflammation, including metabolic inflammation, with mixed results.
Joseph C. Lownik, Jared S. Farrar, Janina V. Pearce, Francesco S. Celi, Rebecca K. Martin   +4 more
doaj   +1 more source

Bone marrow adipocytes [PDF]

Adipocyte, 2017
Adipocytes were identified in human bone marrow more than a century ago, yet until recently little has been known about their origin, development, function or interactions with other cells in the bone marrow. Little functional significance has been attributed to these cells, a paradigm that still persists today. However, we now know that marrow adipose
Mark C, Horowitz, Ryan, Berry, Brandon, Holtrup, Zachary, Sebo, Tracy, Nelson, Jackie A, Fretz, Dieter, Lindskog, Jennifer L, Kaplan, Gene, Ables, Matthew S, Rodeheffer, Clifford J, Rosen   +10 more
openaire   +2 more sources

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

Adipocyte, 2019
Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect.
Md Abu Bakkar Siddik, Bhaskar C. Das, Louis Weiss, Nikhil V. Dhurandhar, Vijay Hegde   +4 more
doaj   +1 more source

Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification

Adipocyte, 2020
The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for quantifying adipocyte size has yet to be standardized.
Anne S Maguire, Lauren N Woodie, Robert L Judd, Douglas R Martin, Michael W Greene, Emily C Graff   +5 more
doaj   +1 more source

Bioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity

Adipocyte, 2022
Obesity is a complex medical condition that affects multiple organs in the body. However, the underlying mechanisms of obesity, as well as its treatment, are largely unexplored.
Yun Yu, Yu-Han Zhang, Liang Liu, Ling-Ling Yu, Jun-Pei Li, Jing-an Rao, Feng Hu, Ling-Juan Zhu, Hui-Hui Bao, Xiao-Shu Cheng   +9 more
doaj   +1 more source