Results 31 to 40 of about 127,948 (310)

Diet-Induced Adipocyte Browning [PDF]

, 2021
The  adipocyte browning process is  a  phenomenon that consists in  the  molecular and  morphological remodeling of  preadipocytes or mature white adipocytes into multilocular beige fat cells expressing thermogenesis-associated genes.
Wiśniewski, Oskar Wojciech, Gibas-Dorna, Magdalena, Szumigała, Agnieszka, Rajczewski, Aleksander   +3 more
core   +1 more source

Transcriptional Activity of PGC-1α and NT-PGC-1α Is Differentially Regulated by Twist-1 in Brown Fat Metabolism

PPAR Research, 2012
Brown fat expresses two PGC-1α isoforms (PGC-1α and NT-PGC-1α) and both play a central role in the regulation of cellular energy metabolism and adaptive thermogenesis by interacting with a wide range of transcription factors including PPARγ, PPARα, ERRα,
Hee-Jin Jun, Thomas W. Gettys, Ji Suk Chang   +2 more
doaj   +1 more source

Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover [PDF]

, 2018
The protective mechanisms of peroxisome proliferator-activated receptor gamma (PPARγ) Pro12Ala polymorphism in type 2 diabetes (T2D) are unclear. We obtained subcutaneous adipose tissue (AT) before and 3 h after oral glucose (OGTT) in carriers and non ...
Maria J. Pereira (4738851), Per Lundkvist (4738848), Gustafsson, Stefan,, Eriksson, Jan W.,, Tove Fall (201258), Castillejo-Lopez, Casimiro, Kamble, Prasad G., Prasad G. Kamble (4738854), Ingelsson, Erik, Fall, Tove,, Pereira, Maria J,, Kamble, Prasad G.,, Castillejo-Lopez, Casimiro,, Lundkvist, Per,, Erik Ingelsson (232651), Lundkvist, Per, Eriksson, Jan W., Ingelsson, Erik,, Casimiro Castillejo-López (394719), Pereira, Maria J, Gustafsson, Stefan, Stefan Gustafsson (418983), Fall, Tove, Jan W. Eriksson (2012872)   +23 more
core   +1 more source

Adipocyte-Specific ACKR3 Regulates Lipid Levels in Adipose Tissue [PDF]

, 2021
Dysfunctional adipose tissue (AT) may contribute to the pathology of several metabolic diseases through altered lipid metabolism, insulin resistance, and inflammation.
Doering, Yvonne, Bayasgalan, Soyolmaa, Vorst, Emiel P. C. van der, Gencer, Selin, Peters, Linsey J. F., Müller, Madeleine, Yvonne Jansen, Jansen, Yvonne, van der Vorst, Emiel P. C., Weber, Christian, Soyolmaa Bayasgalan, Selin Gencer, Madeleine Müller, Döring, Yvonne, Mueller, Madeleine, Yvonne Döring, Emiel P. C. van der Vorst, Linsey J. F. Peters, Olga Schengel, Schengel, Olga, Christian Weber   +20 more
core   +1 more source

Adipocyte Secretome Increases Radioresistance of Malignant Melanocytes by Improving Cell Survival and Decreasing Oxidative Status [PDF]

, 2017
Radiotherapy is a treatment option for the majority of malignancies. However, because melanoma is known to be radioresistant, the use of ionizing radiation as an adjuvant therapy in cutaneous melanoma patients is ineffective.
Vieira, Mónica, Faria, Isabel, Soares, Raquel, Isabel Faria, Gabriela Pinto, Coelho, Pedro, Monteiro, Armanda, Mónica Vieria, Silva, Liliana, Cristina Prudêncio, Rúben Fernandes, Pinto, Gabriela, Prudêncio, Cristina, Armanda Monteiro, Fernandes, Rúben, Pedro Coelho, Liliana Silva, Raquel Soares   +17 more
core   +2 more sources

Welcome toAdipocyte [PDF]

Adipocyte, 2012
When Ron Landes approached me last summer with the idea to launch a journal dedicated to adipose tissue research, it resonated immediately; I loved the idea. Thus, it is with great pleasure that we launch Adipocyte, the first international peer-reviewed multi-disciplinary journal to focus exclusively on research covering all aspects of adipose tissue ...
openaire   +2 more sources

Promotion of lipid storage rather than of thermogenic competence by fetal versus newborn calf serum in primary cultures of brown adipocytes [PDF]

, 2018
Much current understanding of brown adipocyte development comes from in-vitro cell models. Serum type may affect the behavior of cultured cells and thus conclusions drawn.
Nedergaard, Jan,, Jan Nedergaard, Jasper M. A. de Jong, de Jong, Jasper M. A.,, Cannon, Barbara,, Barbara Cannon   +5 more
core   +1 more source

High levels of dietary methionine improves sitagliptin-induced hepatotoxicity by attenuating oxidative stress in hypercholesterolemic rats

Nutrition & Metabolism, 2020
Background Both cholesterol (Cho) and methionine (Met, a precursor for homocysteine) are risk factors for fatty liver disease. Since Western diets are rich in Cho and Met, we investigated the hepatic effects of feeding a diet enriched in Met and Cho ...
Avinash Kumar, Rashmi Pathak, Henry A. Palfrey, Kirsten P. Stone, Thomas W. Gettys, Subramanyam N. Murthy   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Control of breast cancer cell growth by adipocyte-released factors. [PDF]

, 2009
Obesity is one of the most challenging and growing health problems, worldwide. Epidemiologic studies now provide compelling evidence that obesity is a risk factor for both cancer incidence and mortality.
FORMISANO, PIETRO
core