Results 11 to 20 of about 127,948 (310)
Weighing in on Adipocyte Precursors [PDF]
Cell Metabolism, 2014 Obesity, defined as an excessive increase in white adipose tissue (WAT), is a global health epidemic. In obesity, WAT expands by increased adipocyte size (hypertrophy) and number (hyperplasia). The location and cellular mechanisms of WAT expansion greatly affect the pathogenesis of obesity.
Berry, Ryan +2 more
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Adipocyte-Specific Disruption of the BBSome Causes Metabolic and Autonomic Dysfunction [PDF]
In this study, we investigated the role of adipocyte BBSome in the regulation of body weight, glucose homeostasis and autonomic cardiovascular function.
Kamal Rahmouni (6848669)
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Adipocyte-secreted IL-6 sensitizes macrophages to IL-4 signaling [PDF]
, 2022 Complex bidirectional crosstalk between adipocytes and adipose tissue immune cells plays an important role in regulating adipose function, inflammation, and insulin responsiveness.
Castle, Joshua P +15 more
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Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism [PDF]
, 2022 Genome-wide association studies identified single nucleotide polymorphisms on chromosome 7 upstream of KLF14 to be associated with metabolic syndrome traits and increased risk for Type 2 Diabetes (T2D).
Qianyi Yang (11961517) +9 more
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Frontiers in Immunology, 2023 IntroductionLipedema is a painful subcutaneous adipose tissue (SAT) disease characterized by adipocyte hypertrophy, immune cell recruitment, and fibrosis in the affected areas.
Philipp Kruppa +14 more
doaj +1 more source
STAT5-Interacting Proteins: A Synopsis of Proteins that Regulate STAT5 Activity
Biology, 2017 Signal Transducers and Activators of Transcription (STATs) are key components of the JAK/STAT pathway. Of the seven STATs, STAT5A and STAT5B are of particular interest for their critical roles in cellular differentiation, adipogenesis, oncogenesis, and ...
Ashley A. Able +2 more
doaj +1 more source
Current Biology, 2014 SummaryIn the United States alone, one-third of adults and nearly one-quarter of children are clinically obese. This growing epidemic is of serious concern as obesity confers a significant risk to developing numerous chronic conditions, including cancer, diabetes, and heart disease. The alarming incidence of obesity and the rising costs of treating the
openaire +2 more sources
COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]
, 1993 Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ +10 more
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Nature Communications, 2023 Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han +15 more
doaj +1 more source
Methods for assessing adipocyte thermogenesis [PDF]
, 2023 Assessing various methods to observe and measure thermal production in mitochondria of brown adipocyte tissue. For the prevention and treatment of obesity and associated metabolic diseases, scientists are studying and discovering how activation of ...
Ezekiel, Blessing
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