Results 71 to 80 of about 282,105 (396)

Adipocyte and adipogenesis

European Journal of Cell Biology, 2013
Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq, Ali, Warren E, Hochfeld, Renier, Myburgh, Michael S, Pepper   +3 more
openaire   +2 more sources

Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy [PDF]

Nutrition & Metabolism, 2007
A major portion of available fatty acids for adipocyte uptake is derived from lipoprotein lipase (LPL)-mediated hydrolysis of circulating lipoprotein particles. In vivo studies aimed at identifying the precise role of adipocyte-derived LPL in fat storage function of adipose tissue have been unable to provide conclusive evidence due to compensatory ...
Orlando Robert A, Gonzales Amanda M
openaire   +3 more sources

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

Cancer & Metabolism, 2017
BackgroundObesity is associated with increased recurrence and reduced survival of breast cancer. Adipocytes constitute a significant component of breast tissue, yet their role in provisioning metabolic substrates to support breast cancer progression is ...
Seher Balaban, Robert F Shearer, Lisa S. Lee, M. van Geldermalsen, Mark Schreuder, Harrison C. Shtein, Rose Cairns, Kristen C. Thomas, D. Fazakerley, T. Grewal, J. Holst, D. Saunders, A. Hoy   +12 more
semanticscholar   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes

Adipocyte
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism.
Yong Geun Jeon, Sun Won Kim, Jae Bum Kim
doaj   +1 more source

The effect of Acot2 overexpression or downregulation on the preadipocyte differentiation in Chinese Red Steppe cattle

Adipocyte, 2020
The quality and nutritional value of beef is closely linked to its content of intramuscular fat (IMF). The differentiation of preadipocytes and the deposition of lipid droplets in the adipocytes are the key to regulate the IMF content.
Lixiang Liu, Jian Wu, Yi Gao, Yang Lv, Jiajia Xue, Lihong Qin, Cheng Xiao, Zhongchang Hu, Lichun Zhang, Xiaotong Luo, Yanli Wang, Yang Cao, Yang Cao, Guoliang Zhang   +13 more
doaj   +1 more source

Noggin depletion in adipocytes promotes obesity in mice. [PDF]

, 2019
ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M, Boström, Kristina I, Fogelman, Alan M, Guo, Yina, Jumabay, Medet, Lusis, Aldons J, Rajbhandari, Prashant, Reue, Karen, Sallam, Tamer, Tontonoz, Peter, Vergnes, Laurent, Wu, Xiuju, Yao, Jiayi, Yao, Yucheng, Zhang, Li   +14 more
core   +1 more source

Cross-Tissue Single-Nucleus RNA Sequencing Discovers Tissue-Resident Adipocytes Involved in Propanoate Metabolism in the Human Heart [PDF]

, 2023
Sankha Subhra Das, Asha Kar, Sandhya Rajkumar, Seung Hyuk Lee, Marcus Alvarez, Kirsi H. Pietiläinen, Päivi Pajukanta   +6 more
openalex   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Role of TLR4 in the induction of inflammatory changes in adipocytes and macrophages

Adipocyte, 2020
In obesity, high levels of saturated fatty acids (SFAs) contribute to adipose tissue inflammation and dysfunction. Obesity-induced macrophage infiltration leads to insulin resistance, but the adipocyte itself may play a role in generating the ...
K. McKernan, M. Varghese, R. Patel, K. Singer   +3 more
doaj   +1 more source