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The roles of PPARs in adipocyte differentiation
Progress in Lipid Research, 2001Adipose tissue development takes place primarily around birth but adipose cell number can increase throughout life in response to nutritional changes. At the molecular level, adipogenesis is the result of transcriptional remodeling that leads to activation of a considerable number of genes.
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2010
Objective: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available regarding the relationship of miRNAs expression profile, biological pathway and cellular phenotype during human ...
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Objective: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available regarding the relationship of miRNAs expression profile, biological pathway and cellular phenotype during human ...
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Hormonal Control of Adipocyte Differentiation and Adipocyte Gene Expression
1988Publisher Summary This chapter presents a summarization of a large number of studies aimed at elucidating the signaling system by which determined cells decide to activate a terminal differentiation program. Using adipogenic cells in culture, it can be documented that the hormonal milieu plays a major role in dictating the decision to trigger ...
G M, Ringold +4 more
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A study of genes involved in adipocyte differentiation
Journal of Pediatric Endocrinology and Metabolism, 2015AbstractWith the use of the microarray technique, genes expressed in the late phase of adipocyte differentiation were investigated. These genes play an important role in stimulating adipocyte growth and lipid droplet formation. Therefore, they contribute a great deal to the onset of obesity.With the use of SW872 adipocytes and the microarray technique,
Shunming, Zhu +3 more
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Adipocytes Migration is Altered Through Differentiation
Microscopy and Microanalysis, 2019AbstractAdipogenesis is a developmental process in which an elongated preadipocyte differentiates to a round adipocyte along with the accumulation of lipid droplets. In the present study, we focus on the study of cell motility at the single-cell level, toward expanding our knowledge regarding the cytoskeleton alteration during differentiation; since ...
Maayan Lustig +4 more
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3-D Adipocyte Differentiation and Peri-adipocyte Collagen Turnover
2014Peri-adipocyte extracellular matrix (ECM) remodeling is a key biological process observed during adipose tissue development and expansion. The genetic loss of a pericellular collagenase, MMP14 (also known as MT1-MMP), renders mice lipodystrophic with the accumulation of undigested collagen fibers in adipose tissues. MMP14 is not necessary for adipocyte
Tae-Hwa, Chun, Mayumi, Inoue
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PPARy in Adipocyte Differentiation
Journal of Animal Science, 1999Adipocytes play a critical homeostatic this process is peroxisome proliferator activated recep- role in energy balance and, more recently, have been tor y (PPARy), a member of the nuclear hormone recognized to function as endocrine cells as well. receptor superfamily that is activated by natural fatty Excess adipocyte mass is a defining feature of ...
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Molecular Mechanisms of Adipocyte Differentiation
Reviews in Endocrine and Metabolic Disorders, 2001Q, Tong, G S, Hotamisligil
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