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Adipocyte Differentiation and Gene Expression
The Journal of Nutrition, 2000The major function of adipocytes is to store triacylglycerol in periods of energy excess and to mobilize this energy during times of deprivation. The short-term control of these lipogenic and lipolytic processes is carefully modulated by hormonal signals from the bloodstream, which provide an inventory of the body's metabolic state.
J M, Ntambi, K, Young-Cheul
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Autophagy in Adipocyte Differentiation
2017Adipose tissue regulates metabolic homeostasis by acting as an endocrine organ and energy reservoir. Adipose tissue development and functional maintenance are dependent on adipocyte differentiation, in which autophagy plays an important role. It has been shown that autophagy deficiency dampens adipocyte differentiation, compromises adipose tissue ...
Zhipeng, Tao +3 more
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2010
Objective: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available regarding the relationship of miRNAs expression profile, biological pathway and cellular phenotype during human ...
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Objective: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available regarding the relationship of miRNAs expression profile, biological pathway and cellular phenotype during human ...
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Hormonal Control of Adipocyte Differentiation and Adipocyte Gene Expression
1988Publisher Summary This chapter presents a summarization of a large number of studies aimed at elucidating the signaling system by which determined cells decide to activate a terminal differentiation program. Using adipogenic cells in culture, it can be documented that the hormonal milieu plays a major role in dictating the decision to trigger ...
G M, Ringold +4 more
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3-D Adipocyte Differentiation and Peri-adipocyte Collagen Turnover
2014Peri-adipocyte extracellular matrix (ECM) remodeling is a key biological process observed during adipose tissue development and expansion. The genetic loss of a pericellular collagenase, MMP14 (also known as MT1-MMP), renders mice lipodystrophic with the accumulation of undigested collagen fibers in adipose tissues. MMP14 is not necessary for adipocyte
Tae-Hwa, Chun, Mayumi, Inoue
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Leiomyomatosis peritonealis disseminata with adipocytic differentiation
Acta Obstetricia et Gynecologica Scandinavica, 1992We report a rare autopsy case of leiomyomatosis peritonealis disseminata in a woman, who had been operated upon for ovarian granulosa cell tumor two years prior to her death. The deposits showed both myofibrohlastic and adipocytic differentiation.
S, Kitazawa, N, Shiraishi, S, Maeda
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Adipocytes Migration is Altered Through Differentiation
Microscopy and Microanalysis, 2019AbstractAdipogenesis is a developmental process in which an elongated preadipocyte differentiates to a round adipocyte along with the accumulation of lipid droplets. In the present study, we focus on the study of cell motility at the single-cell level, toward expanding our knowledge regarding the cytoskeleton alteration during differentiation; since ...
Maayan Lustig +4 more
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Adipocyte differentiation from the inside out
Nature Reviews Molecular Cell Biology, 2006Improved knowledge of all aspects of adipose biology will be required to counter the burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the past few years with emphasis on the intersection between extracellular signals and the transcriptional cascade that regulates adipocyte differentiation.
Evan D, Rosen, Ormond A, MacDougald
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PPARy in Adipocyte Differentiation
Journal of Animal Science, 1999Adipocytes play a critical homeostatic this process is peroxisome proliferator activated recep- role in energy balance and, more recently, have been tor y (PPARy), a member of the nuclear hormone recognized to function as endocrine cells as well. receptor superfamily that is activated by natural fatty Excess adipocyte mass is a defining feature of ...
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Extracellular redox environments regulate adipocyte differentiation
Differentiation, 2010Oxidized extracellular redox states have been associated with many diseases related to obesity, including heart disease and diabetes, but relatively little is known about the relationship between extracellular redox states and obesity. In 3T3-L1 preadipocytes, oxidizing extracellular redox potentials (E(h)) increased intracellular and mitochondrial ...
Barry R, Imhoff, Jason M, Hansen
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