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Regulation of Adipocyte Differentiation

Annals of Medicine, 2001
Once multipotent mesenchymal cells become committed to the adipoblast lineage, adipogenesis, the process of preadipocytes differentiation into adipocytes is initiated. This process starts with a phase of exponential growth of adipoblasts. Following confluence of these adipoblasts, the cells enter into a cell cycle arrest, they re-enter the cell cycle ...
Johan Auwerx, Hana Koutníková
exaly   +6 more sources

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Molecular Regulation of Adipocyte Differentiation

Seminars in Cell and Developmental Biology, 1999
Significant advances have been made recently toward understanding the molecular events that regulate adipocyte differentiation. In vitro models of adipogenesis, such as the 3T3-L1 and F-442A preadipocyte cell lines have proven to be an invaluable resource in elucidating mechanisms of adipocyte differentiation. Subject to modulation by hormonal, dietary,
Robert E Lyle, R E McGehee, Robert M Cowherd   +2 more
exaly   +3 more sources

Transcriptional Repression of Type I Procollagen Genes During Adipocyte Differentiation

Experimental and Molecular Medicine, 2001
isobutylmethylxanthine; ORO, oil red O Adipocyte differentiation is a very complex process in which whole-cell changes are accompanied. Among them, type I procollagen gene has been shown to specifically decrease during adipocyte differentia-tion; however,
In-San Kim, Rang-Woon Park, T Yi
exaly   +1 more source

microRNAs regulate adipocyte differentiation

Cell Biology International, 2013
AbstractThe number of adipocytes is relevant to the extent of differentiation from pluripotent stem cells into pre‐adipocytes, whereas the size of adipocytes relates to the extent of differentiation from pre‐adipocytes into mature fat cells and the accumulation of triglyceride.
Lin, Chen, Jinlin, Song, Junhui, Cui, Jia, Hou, Xiaohui, Zheng, Cai, Li, Lei, Liu   +6 more
openaire   +2 more sources

Autophagy in Adipocyte Differentiation

2017
Adipose tissue regulates metabolic homeostasis by acting as an endocrine organ and energy reservoir. Adipose tissue development and functional maintenance are dependent on adipocyte differentiation, in which autophagy plays an important role. It has been shown that autophagy deficiency dampens adipocyte differentiation, compromises adipose tissue ...
Zhipeng, Tao, Longhua, Liu, Louise D, Zheng, Zhiyong, Cheng   +3 more
openaire   +2 more sources

The role of microRNAs in adipocyte differentiation

Frontiers of Medicine, 2013
Adipocytes differentiate from mesenchymal stem cells (MSCs) in a process known as adipogenesis. The programme of adipogenesis is regulated by the sequential activation of transcription factors and several signaling pathways. There is growing evidence indicating that a class of small non-coding single-stranded RNAs known as "microRNAs (miRNAs)" also are
Rong, Zhang, Di, Wang, Zhuying, Xia, Chao, Chen, Peng, Cheng, Hui, Xie, Xianghang, Luo   +6 more
openaire   +2 more sources

Adipocyte Differentiation and Gene Expression

The Journal of Nutrition, 2000
The major function of adipocytes is to store triacylglycerol in periods of energy excess and to mobilize this energy during times of deprivation. The short-term control of these lipogenic and lipolytic processes is carefully modulated by hormonal signals from the bloodstream, which provide an inventory of the body's metabolic state.
J M, Ntambi, K, Young-Cheul
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The Role of MAPKs in Adipocyte Differentiation and Obesity [PDF]

Biochimie, 2005
The ERK, p38 and JNK mitogen activated protein kinases (MAPKs) are intracellular signalling pathways that play a pivotal role in many essential cellular processes such as proliferation and differentiation. MAPKs are activated by a large variety of stimuli and one of their major functions is to connect cell surface receptors to transcription factors in ...
Bernard Binetruy, Leslie Caron, Frédéric Bost   +2 more
exaly   +4 more sources

Using differential display in the study of adipocyte differentiation

Biochemical Society Transactions, 1994
Study of the programme of adipose conversion displayed by mouse 3T3L1 adipocyte precursors and control 3T3C2 cells [l-31 using the recently developed differential display [4-61 technique have been initiated. The two 3T3 fibroblast cell sub-lines differ in their ability to develop the biochemical characteristics of mature adipocytes and the process can ...
W D, Edwards, H L, Jessop, A, Cryer
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