Results 151 to 160 of about 267,086 (349)
Nature Communications, 2015 Marrow adipose tissue (MAT) accumulates in diverse clinical conditions but remains poorly understood. Here we show region-specific variation in MAT adipocyte development, regulation, size, lipid composition, gene expression and genetic determinants ...
E. Scheller +15 more
semanticscholar +1 more source
CellsObesity is a growing global health concern, contributing to diseases such as cancer, autoimmune disorders, and neurodegenerative conditions. Adipose tissue dysfunction, characterized by abnormal adipokine secretion and chronic inflammation, plays a key role in these conditions.
Mangesh Dattu Hade +10 more
openaire +3 more sources
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
The Anatomical Record, EarlyView.Comparative histological and semi‐automated image analysis of primate lips: Masson's trichrome‐stained sagittal sections were segmented to quantify the connective tissue, adipose, and muscular components, enabling interspecific comparisons of labial architecture.
Liat Rotenstreich +5 more
wiley +1 more source
Plasticity of Thermogenic Adipocytes
, 2018 Adipocytes are mesenchymal cells specialized in storing large quantities of lipids in the cytosol as lipid droplets. They are found in adipose tissues such as those found subcutaneously or intraabdominally, as well as in many smaller depots within or ...
Andersen, Maja Worm +2 more
core +2 more sources
The role of endoplasmic reticulum in human adipose tissue [PDF]
Adipose tissue plays a central role in the regulation of metabolic homeostasis. In obesity adipocytes are challenged by many insults: surplus energy, inflammation, insulin resistance and considerable endoplasmic reticulum (ER) stress.
Alhusaini, S. (Saif)
core
, 2014 Panel A, (a), Cells were exposed to antalarmin (a CRF1 receptor antagonist) and/or astressin-2B (a CRF2 receptor antagonist) and the decrease of specific binding activity was measured.
John Melissas (565532) +6 more
core +1 more source
Animal Research and One Health, EarlyView.This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang +9 more
wiley +1 more source
Adipocyte, 2019 White adipose tissue (WAT) nucleated stromal cells (NSC) play important roles in regulation, defense, regeneration and metabolic control. In WAT sites, the proportions and functions of NSC change under diverse physiological or pathologic conditions.
Floriana Rotondo +5 more
doaj +1 more source