Results 141 to 150 of about 60,035 (184)

Association Between BMI and the Efficacy and Safety of CDK4/6 Inhibitors in HR+/HER2− Advanced Breast Cancer: A Multicenter Retrospective Propensity Score Matched Cohort Study (CAMELIA)

open access: yesMedComm – Oncology, Volume 5, Issue 4, December 2026.
This multicenter real‐world study showed that higher BMI (≥ 25 kg/m2) was independently associated with improved PFS in patients with HR+/HER2− advanced breast cancer receiving CDK4/6 inhibitors. Safety outcomes were comparable between BMI groups, and the findings were consistent across alternative BMI thresholds, suggesting the potential prognostic ...
Min Tian   +12 more
wiley   +1 more source

Potential Role for the Ubiquitin Ligase SIAH2 in Modulating Bone Morphology and Adiposity. [PDF]

open access: yesCalcif Tissue Int
Scott MC   +4 more
europepmc   +1 more source

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang   +6 more
wiley   +1 more source

Preliminary Evidence Suggests the Transcriptomic Response of Tricolored Bats to White‐Nose Syndrome Is Similar but Not Identical to That of Little Brown Bats

open access: yesEcology and Evolution, Volume 16, Issue 11, November 2026.
In this study, we evaluate gene expression of tricolored bats in response to white‐nose syndrome and compare it to that of little brown bats. We found that tricolored bats show evidence of a similar transcriptomic immune response to little brown bats, sharing pathways and some genes.
Robert E. Kwait   +5 more
wiley   +1 more source

Renin–Angiotensin System Activation Drives Early Cardiorenal Dysfunction in Normotensive Prediabetes

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Increased angiotensin‐converting enzyme 1 (ACE1) expression in perivascular and perirenal adipose tissues of prediabetic rats contributes to early cardiovascular and cardiorenal deterioration in the absence of obesity and hypertension. Systemic Angiotensin II exacerbates the observed detrimental effects of prediabetes.
Nour‐Mounira Z. Bakkar   +6 more
wiley   +1 more source

Comparative analysis of select 3D human mesenchymal stromal cell-derived spheroid models for adipogenic differentiation. [PDF]

open access: yesAdipocyte
Vezzani B   +5 more
europepmc   +1 more source

E3 ligase FBXO2-mediated protein stability of insulin receptor regulates adipogenesis and metabolic health in obesity. [PDF]

open access: yesCell Death Dis
Xin Y   +16 more
europepmc   +1 more source

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