Results 151 to 160 of about 60,035 (184)

Long Non‐Coding RNAs: Key Regulators of Economic Traits in Livestock From Mechanisms to Breeding Applications

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani   +2 more
wiley   +1 more source

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

open access: yesCancer Science, Volume 117, Issue 11, Page 3007-3021, November 2026.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon   +6 more
wiley   +1 more source

Myeloid‐Derived Growth Factor Alleviates Diabetic Non‐Alcoholic Fatty Liver Disease by Up‐Regulating ABCA1 and ABCG1 Expression via the AMPK/PPARγ/LXRα Pathway

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT The regulatory role of bone marrow in systemic metabolic processes remains incompletely characterized. Myeloid‐derived growth factor (MYDGF) is a myeloid cell‐secreted factor with emerging metabolic functions, but its action in diabetes‐associated non‐alcoholic fatty liver disease (DM NAFLD) is undefined.
Zeyu Chen   +3 more
wiley   +1 more source

Single‐Cell Transcriptomics Reveals the FA9–VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

open access: yesPlant Biotechnology Journal, Volume 24, Issue 11, Page 5812-5829, November 2026.
ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue (FA9) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean.
Hui Li   +14 more
wiley   +1 more source

Endothelial Matrin‐3 Limits Cellular Senescence and Lipid Dysregulation to Protect Against Murine Atherosclerosis

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng   +5 more
wiley   +1 more source

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