Results 101 to 110 of about 69,441 (277)

New potential fat marker genes, selected based on the coupling model of adipogenesis and reverse adipogenesis.

, 2013
Gene expression analysis was performed using qRT-PCR and the expression values were normalized to GAPDH for stepwise assessment of adipogenesis and reverse adipogenesis (dedifferentiation). Gene expression of new potential fat marker genes (A) APCDD1, (B)
Jochen Ringe (46862), Thomas Häupl (18992), Stefan Stich (438448), Jan Eucker (427775), Mujib Ullah (438447), Michael Sittinger (883)   +5 more
core   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

Adipogenesis 에서 Nupr1 의 역할

, 2022
선진국의 비만율 증가는 제 2 형 당뇨병, 심혈관 질환 등과 같은 대사 질환의 발생 증가와 상관관계가 있기 때문에 심각한 문제로 대두되고 있다. 지방세포분화 조절 메커니즘은 비만과 같은 신진대사 질환과의 상관관계 때문에 널리 연구되는 주제이다. 그러므로, 지방세포분화를 조절하는 생물학적 네트워크를 연구하는 것은 비만의 병리생리학에 대한 더 큰 이해를 가져올 수 있다. 지방세포 분화는 초기 지방 분화와 후기 지방 분화과정을 거친다.
MENDES DUARTE TATIANA PATRICIA
core  

Polypeptide N-acetylgalactosaminyltransferase-15 regulates adipogenesis in human SGBS cells

Scientific Reports
Adipogenesis involves intricate molecular mechanisms regulated by various transcription factors and signaling pathways. In this study, we aimed to identify factors specifically induced during adipogenesis in the human preadipocyte cell line, SGBS, but ...
Asuka Takahashi, Ryo Koike, Shota Watanabe, Kyoko Kuribayashi, Martin Wabitsch, Masahiko Miyamoto, Akihiko Komuro, Mineaki Seki, Masayuki Nashimoto, Akiko Shimizu-Ibuka, Kikuji Yamashita, Takeo Iwata   +11 more
doaj   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15

Cell Reports, 2017
The generation of new adipocytes from precursor cells (adipogenesis) has implications for systemic metabolism and is a commonly used model for studying the process of cell differentiation in vitro.
Abhishek Aggarwal, Maria José Costa, Belén Rivero-Gutiérrez, Lijuan Ji, Stefanie L. Morgan, Brian J. Feldman   +5 more
doaj   +1 more source

TGF‐β effects on adipogenesis of 3T3‐L1 cells differ in 2D and 3D cell culture conditions

FEBS Open Bio
The TGF‐β superfamily plays a pivotal role in the regulation of adipogenesis, but little is known about the potential differential role of the three isoforms of TGF‐β, TGF‐β‐1~3.
Araya Umetsu, Megumi Watanabe, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro   +6 more
doaj   +1 more source

Nuclear MEK1 sequesters PPARγ and bisects MEK1/ERK signaling: a non-canonical pathway of retinoic acid inhibition of adipocyte differentiation.

PLoS ONE, 2014
Uncontrolled adipogenesis and adipocyte proliferation have been connected to human comorbidities. Retinoic acid (RA) is known to inhibit adipocyte differentiation, however the underlying mechanisms have not been adequately understood.
Sandeep Dave, Ravikanth Nanduri, Hedwin Kitdorlang Dkhar, Ella Bhagyaraj, Alka Rao, Pawan Gupta   +5 more
doaj   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

Homocysteine inhibits adipogenesis in 3T3-L1 preadipocytes

, 2011
Hyperhomocysteinemia (HHcy) is a characteristic metabolic abnormality in several pathological conditions, including hypertension, diabetes and alcoholic liver disease. Emerging evidence indicates that adipose tissue contributes to HHcy and homocysteine (
Zhigang Wang, Xiaobing Dou, Zhenyuan Song, Tong Yao   +3 more
core   +1 more source