Results 101 to 110 of about 94,652 (323)
Molecules, 2019 Obesity is recognized as a worldwide health crisis. Obesity and its associated health complications such as diabetes, dyslipidemia, hypertension, and cardiovascular diseases impose a big social and economic burden.
Eugene Chang, C. Kim
semanticscholar +1 more source
Transcriptional Regulation of Adipogenesis by KLF4 [PDF]
, 2008 SummaryWhile adipogenesis is known to be controlled by a complex network of transcription factors, less is known about the transcriptional cascade that initiates this process.
Friedman, Jeffrey +5 more
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Adipogenesis-related microRNAs in obesity
, 2022 © ExRNA. All rights reserved.In the last four decades, studies have shown that the significant increase in the prevalence of obesity has become a pandemic. While obesity decreases life expectancy, it largely increases healthcare expenditures. However, up
ENGİN, AYŞE BAŞAK +3 more
core +1 more source
Identification of BCL11B as a regulator of adipogenesis [PDF]
Scientific Reports, 2016 AbstractThe differentiation of preadipocytes into adipocytes is controlled by several transcription factors, including peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer-binding protein α (C/EBPα), which are known as master regulators of adipogenesis.
Jun Inoue +10 more
openaire +2 more sources
Advanced Science, EarlyView.Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su +14 more
wiley +1 more source
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation
Cell Death and Disease, 2022 Adipogenesis is a complex cascade involved with the preadipocytes differentiation towards mature adipocytes, accelerating the onset of obesity. Histone methyltransferase SET and MYND domain-containing protein 2 (Smyd2), is involved in a variety of ...
Haibi Su +5 more
doaj +1 more source
Long non-coding RNAs in regulation of adipogenesis and adipose tissue function
eLife, 2020 Complex interaction between genetics, epigenetics, environment, and nutrition affect the physiological activities of adipose tissues and their dysfunctions, which lead to several metabolic diseases including obesity or type 2 diabetes. Here, adipogenesis
T. Squillaro +3 more
semanticscholar +1 more source
Metalloproteases and Adipogenesis: A Weighty Subject [PDF]
The American Journal of Pathology, 2002 Obesity has become a prevalent health hazard in industrialized countries and is closely associated with a number of pathological disorders such as cancer, cardiovascular disease, hypertension, and non-insulin-dependent diabetes. 1 Even with such serious health implications there is still a great deal to learn before we can fully understand the ...
Jennifer, Lilla +2 more
openaire +2 more sources
Advanced Science, EarlyView.This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Stem cell research & therapeutics, 2019 Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into several tissues, such as bone, cartilage, and fat. Glucocorticoids affect a variety of biological processes such as proliferation, differentiation, and apoptosis of ...
Li-zhi Han +5 more
semanticscholar +1 more source