Results 111 to 120 of about 69,441 (277)

Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation

Cells
The ongoing obesity epidemic has raised awareness of the complex physiology of adipose tissue. Abnormal adipocyte differentiation results in the development of systemic metabolic disorders such as insulin resistance and diabetes. The conjugation of NEDD8
Hongyi Zhou, Vijay Patel, Robert Rice, Richard Lee, Ha Won Kim, Neal L. Weintraub, Huabo Su, Weiqin Chen   +7 more
doaj   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Regulation of mitophagy by Sab during adipogenesis

, 2015
Obesity is a global epidemic. Adipogenesis, the synthesis of fat, is elevated in obese individuals. During adipogenesis, mitochondrial density is reduced by a form of self-digestion called mitophagy.
Goubert, Désirée
core   +1 more source

Inhibition of ASCT2 is essential in all‐trans retinoic acid‐induced reduction of adipogenesis in 3T3‐L1 cells

FEBS Open Bio, 2015
Vitamin A has preventive effects on obesity. All‐trans retinoic acid (ATRA), the active form of vitamin A, inhibits lipid accumulation in 3T3‐L1 cells in an experimental adipogenesis model.
Katsuhiko Takahashi, Natsumi Uchida, Chisato Kitanaka, Chiaki Sagara, Masahiko Imai, Noriko Takahashi   +5 more
doaj   +1 more source

Prolactin and Triiodothyronine Modulate Seasonal Variation in Brown Adipose Tissue in Djungarian Hamsters

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Seasonal photoperiodic cycles regulate energy rheostasis in many animals. Brown adipose tissue (BAT) and the liver are key metabolic organs that show remarkable plasticity in response to photoperiodic conditions. Prolactin (PRL) and thyroid hormones are endocrine signals that transmit neural‐derived photoperiodic time measurement encoding to ...
Sayantan Sur, Grace Payling, Calum Stewart, Avalene Tan, Caitlin Diggle, Tyler J. Stevenson   +5 more
wiley   +1 more source

The inhibitory effects of Xiao-Gao-Jiang-Zhuo-containing serum on adipogenesis in 3T3-L1 preadipocytes

Background. Obesity and related metabolic diseases are becoming a worldwide epidemic, leading to increased mortality and heavy medical costs. Our Chinese herbal formula Xiao-Gao-Jiang-Zhuo (XGJZ) has remarkable effects on curing obese patients in the ...
Chen Chen, Jing Li, Liang Chen, Chunpeng Feng, Ting Ye, Yu Han   +5 more
core   +1 more source

Gsα signalling suppresses PPARγ2 generation and inhibits 3T3L1 adipogenesis

, 2009
Since TSH receptor (TSHR) expression increases during adipogenesis and signals via cAMP/phospho-cAMP-response element binding protein (CREB), reported to be necessary and sufficient for adipogenesis, we hypothesised that TSHR activation would induce ...
Ludgate, Marian Elizabeth, Lewis, Mark David, Lewis, M.D., Ludgate, M., Zhang, L., Grennan-Jones, Fiona Antoinette, Zhang, Lei, Paddon, C., Grennan-Jones, F., Paddon, Carol Ann   +9 more
core   +1 more source

The Application of Duck Embryonic Fibroblasts CCL-141 as a Cell Model for Adipogenesis

Animals
The duck embryo fibroblast cell line CCL-141, which is currently the only commercialized duck cell line, has been underexplored in adipogenesis research.
Dan-Dan Sun, Xiao-Qin Li, Yong-Tong Liu, Meng-Qi Ge, Zhuo-Cheng Hou   +4 more
doaj   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori, Pedro Garcia Caparros, Antonella Castagna, Luisa Custódio, Valentina Lazazzara, Claus Krogh Madsen, Felicia Menicucci, Maria João Rodrigues, Katalin Solymosi, Jose Ramon Acosta Motos   +9 more
wiley   +1 more source

Osteoprotegerin mediates adipogenesis in obesity

Introduction: Adipogenesis, the process of white adipose tissue expansion, plays a critical role in the development of obesity. Osteoprotegerin (OPG), known for its role in bone metabolism regulation, emerges as a potential regulator in mediating ...
Lidan Zhong, Linda, Chan, Yau-Tuen, Zhang, Cheng, Lu, Yuanjun, Xu, Lin, Wang, Ning, Wu, Xingyao, Wu, Junyu, Yang, Wei, Lyu, Zipan, Fung Lam, Tsz, Zhong, Linda Lidan, Chan, Yau Tuen, Lam, Tsz Fung   +13 more
core   +1 more source