Results 111 to 120 of about 94,652 (323)
Adipocyte, 2020 Given the high and increasing prevalence of obesity and associated disorders, such as type-2 diabetes, it is important to understand the mechanisms that regulate lipid storage and the differentiation of fat cells, a process termed adipogenesis. Using the
James E. Merrett +3 more
doaj +1 more source
Scientific Reports, 2020 To establish a deepening of the upper eyelid sulcus (DUES) model that can be induced by prostaglandin (PG) analogues, a three-dimension (3D) tissue culture was employed.
Yosuke Ida +4 more
semanticscholar +1 more source
Regulation of adipogenesis by nucleotides
Biochemical Society TransactionsThe process by which multipotent cells commit to differentiate into distinct cell types, eventually forming functional tissues and organisms, has fascinated scientists for decades. Consequently, numerous studies have contributed to our understanding of how transcription factors and signaling molecules regulate differentiation.
Julia A. Pinette +3 more
openaire +2 more sources
Advanced Science, EarlyView.As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia +13 more
wiley +1 more source
AMP-Activated protein kinase and epigenetic modifications governing adipogenesis [PDF]
, 2016 Obesity is a worsening problem affecting a large proportion of world population. Especially, the percentage of obese women dramatically climbed in the past three decades.
Yang, Qiyuan
core +4 more sources
Advanced Science, EarlyView.Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu +18 more
wiley +1 more source
Involvement of calcium channels in the regulation of adipogenesis
Adipocyte, 2020 As an important second messenger in adipocytes, calcium ions (Ca2+) are essential in regulating various intracellular signalling pathways that control critical cellular functions.
Ming-Zhu Zhai +3 more
semanticscholar +1 more source
Characterisation of adipocyte-derived extracellular vesicles released pre- and post-adipogenesis
, 2015 Extracellular vesicles (EVs) are submicron vesicles released from many cell types, including adipocytes. EVs are implicated in the pathogenesis of obesity-driven cardiovascular disease, although the characteristics of adipocyte-derived EVs are not well ...
D Aled Rees (10871627) +8 more
core
TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma
Advanced Science, EarlyView.TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin +9 more
wiley +1 more source
, 2016 Several transcription factor identified in the regulators study and one gene upregulated in Iberian pigs are involved in the adipogenesis pathway, most of them regulate PPARg expression or activation.
Ana I. Rey (3391574) +11 more
core +2 more sources