Results 131 to 140 of about 36,549 (313)

Exometabolomics Reveals Metabolic Modulation Induced by Chia Oil Supplementation in Adipose Tissue Explants From Obese Mice

Lipids, EarlyView.
The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr, Agatha Assis‐Ferreira, Gabrielly Muniz‐Cassuce, Tatiana El Bacha, Christina Barja‐Fidalgo, Simone Vargas da Silva   +5 more
wiley   +1 more source

Serum adipokine levels in rheumatoid arthritis patients and their contributions to the resistance to treatment.

, 2014
The aim of this study was to determine whether disease activity and the type of therapy differentially modulate serum adipokine levels in patients with rheumatoid arthritis (RA), and whether pre-therapy adipokine levels contribute to resistance to ...
이수곤, 박용범
core   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Performance of an adipokine pathway-based multilocus genetic risk score for prostate cancer risk prediction.

, 2012
Few biomarkers are available to predict prostate cancer risk. Single nucleotide polymorphisms (SNPs) tend to have weak individual effects but, in combination, they have stronger predictive value.
Agnihotram V Ramanakumar, Rui M. Medeiros (153655), Francisco M Pina, Carlos M. S. Lopes, Azevedo, ASM, Rui M Medeiros, Agnihotram V. Ramanakumar, Eduardo L Franco, Virgínia F M Cunha, Agnihotram V. Ramanakumar (153643), Eduardo L. Franco (153658), Avelino M. Fraga (153647), Francisco M. Pina, Cátia P. D. Monteiro, Virgínia F. M. Cunha, Cátia P D Monteiro, Carlos M S Lopes, Avelino M. Fraga, Rui M. Medeiros, Andreia S. M. Azevedo, Avelino M Fraga, Carlos M. S. Lopes (153651), Ricardo J. T. Ribeiro (153629), Eduardo L. Franco, Ricardo J T Ribeiro, Cátia P. D. Monteiro (153631), Andreia S M Azevedo, Virgínia F. M. Cunha (153639), Francisco M. Pina (153649), Ricardo J. T. Ribeiro, Andreia S. M. Azevedo (153636)   +30 more
core   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Identification of nesfatin-1 in human and murine adipose tissue: a novel depot-specific adipokine with increased levels in obesity

, 2010
Nesfatin-1 is a recently identified anorexigenic peptide derived from its precursor protein, non-esterified fatty acid/nucleobindin 2 (NUCB2). Although the hypothalamus is pivotal for the maintenance of energy homeostasis, adipose tissue plays an ...
Patel, Suketu, Lehnert, H., Tan, Bee K., Hallschmid, Manfred, Tripathi, Gyanendra, Tan, B.K., Randeva, Harpal S., Hillhouse, E.W., Hallschmid, M., Chen, J., Ramanjaneya, M., Kern, Werner, Brown, James E. P., Kern, W., Hillhouse, Edward W., Randeva, H.S., Ramanjaneya, Manjunath, Tripathi, G., Patel, S., Chen, Jing, Lehnert, Hendrik, Brown, J.   +21 more
core   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, EarlyView.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source

The Plasma Levels of Protein Adiponectin (AdipoQ) and Meteorin-Like (Metrnl) in Newly Diagnosed Type 2 Diabetes Mellitus

Diabetes, Metabolic Syndrome and Obesity
Lan Dam Thi Phuong,1,2 Thinh Tran Huy,1 Thuan Huynh Quang2 1Biochemistry Department, Hanoi Medical University, Hanoi, Vietnam; 2Department of Biochemistry, 103 Military Hospital, Vietnam Military Medical University, Hanoi, VietnamCorrespondence: Thuan ...
Phuong LDT, Tran Huy T, Huynh Quang T
doaj  

Is PBEF/Visfatin/Nampt an authentic adipokine relevant to the metabolic syndrome?

, 2007
Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Their dysregulated production in obesity has implicated them as important mediators in the pathogenesis of obesity-related risk factors for diabetes and ...
Jaswinder K. Sethi, Sethi, Jaswinder K.
core   +1 more source

Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu, Lee‐Yuan Lin, Jia‐Wei Sun, Wei‐Ting Yu, Fara Silvia Yuliani, Shyh‐Hsiang Lin   +5 more
wiley   +1 more source