Results 141 to 150 of about 52,905 (310)

The Temporal Expression of Adipokines During Spinal Fusion [PDF]

, 2017
Background Context Adipokines are secreted by white adipose tissue and have been associated with fracture healing. Our goal was to report the temporal expression of adipokines during spinal fusion in an established rabbit model.
Bertone, Alicia L., Hussein, Hayam Hamaz, Kaido, Mari, Khan, Safdar, Toth, Jeffrey M., Virk, Sohrab   +5 more
core   +1 more source

The Impact of Obesity on Durable Left Ventricular Assist Device Implantation: A Systematic Review and Meta‐Analysis

Artificial Organs, EarlyView.
14 100 LVAD patients across 21 studies were analyzed. Findings indicated that obese LVAD recipients had lower short‐term mortality and higher risk of infection, thrombosis and right heart failure. There was no difference in long‐term survival between obese and non‐obese patients.
Hugh Jacobs, Olivia Frost, Arian Arjomandi Rad, Wing Kiu Chou, Sadeq Al‐Saegh, Alina Zubarevich, Alexander Weymann, Arjang Ruhparwar, Lukman Amanov, Peyman Sardari Nia, Antonios Kourliouros, Thanos Athanasiou   +11 more
wiley   +1 more source

Sarcopenia Is Associated With Mortality and Progression of Cirrhosis in Decompensated but Not Compensated Disease—A Multicentre Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective cohort of 1,624 adults with cirrhosis, sarcopenia was independently associated with unplanned hospitalization, death, and cirrhosis progression (or death) in patients with decompensated disease. In compensated cirrhosis, sarcopenia was associated only with a higher risk of unplanned hospitalization.
Puneeta Tandon, Sarah Wang, Moon Young Kim, Bart Van Hoek, Daphne Bot, Jeroen L. A. van Vugt, Berend Beumer, Jan Ijzermans, Sunil Taneja, Ajay Duseja, Surender Singh, Maryam Ebadi, Aldo J. Montano‐Loza   +12 more
wiley   +1 more source

Functional Implications of DNA Methylation in Adipose Biology. [PDF]

, 2019
The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
core  

Circulating levels of insulin‐like growth factor I (IGF‐I) and risk of multiple myeloma: An observational and Mendelian randomisation study

British Journal of Haematology, EarlyView.
Summary Evidence for an association between insulin‐like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF‐I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two‐sample Mendelian randomisation (MR) analysis using identified ...
Yolanda Benavente, Sara Hermosa, Nikos Papadimitriou, Alyssa Clay‐Gilmour, Elizabeth E. Brown, Jonathan N. Hofmann, Nathaniel Rothman, Qing Lan, Sonja I. Berndt, Demetrius Albanes, Mark Purdue, Mitchell J. Machiela, Stephen J. Chanock, Parveen Bhatti, Wendy Cozen, Aaron Norman, Susan L. Slager, James R. Cerhan, Vincent Rajkumar, Shaji K. Kumar, Celine M. Vachon, Anne J. Novak, Thomas M. Habermann, Brian K. Link, Gilles Salles, Herve Ghesquieres, Paige M. Bracci, Elizabeth Holly, Rosalie G. Griffin, Michelle A. T. Hildebrandt, Roel C. H. Vermeulen, P. Martijn Kolijn, Henrik Hjalgrim, Karin Ekström Smedby, Harindra Jayasekara, Simon Cheah, Alain Monnereau, Yu Chen, Alan Arslan, Yawei Zhang, Nicola J. Camp, Douglas W. Sborov, Afaf E. G. Osman, Elad Ziv, Immaculata De Vivo, Vijai Joseph, Lauren R. Teras, Alpa V. Patel, Eleanor Kane, Claire M. Vajdic, Adrien Guilloteau, Pierluigi Cocco, Laia Alemany, Juan Sainz, James McKay, Brenda M. Birmann, Delphine Casabonne   +56 more
wiley   +1 more source

Associations Between Serum Adipokine, Antipsychotic Exposure, and Clinical Characteristics in Chronic Schizophrenia: A Cross‐Sectional Study [PDF]

Neuropsychopharmacol Rep
In chronic schizophrenia, serum adiponectin levels were positively associated with antipsychotic dosage, particularly with multi‐acting receptor‐targeted antipsychotics and were influenced by gender and hospitalization period. These findings highlight gender‐specific metabolic regulation and the importance of monitoring adipokines during long‐term ...
Ohno Y, Saito K, Hanabusa K, Nakai A, Nagai T, Hida N, Sanada K.   +6 more
europepmc   +2 more sources

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

British Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, William B. Campbell, Scott P. Levick   +11 more
wiley   +1 more source

Editorial: The roles and mechanisms of hepatokines, adipokines and myokines in the development of non-alcoholic fatty liver disease (NAFLD)

Frontiers in Endocrinology, 2022
Yan Lu
doaj   +1 more source

Frequency of Polymorphisms of rs2274907 of Omentin Gene and rs9770242 of Visfatin Gene in Non-Alcoholic Fatty Liver Disease in an Iranian Population [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Non-alcoholic fatty liver disease is the most common chronic disease, frequently occurring in various instances; if left undiagnosed and untreated, it will progress to cirrhosis and, in some cases, result in death.
Mahnaz Mohammadi, Neda kolivand saloki
doaj  

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source