Results 151 to 160 of about 52,905 (310)
Clinical Obesity, Volume 15, Issue 2, April 2025.Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source
Therapeutics and Clinical Risk ManagementMianxian Li,1,* Shuru Zhou,2,* Zexiong Feng,1,* Chi Zhang1 1Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2The Aoyang Cancer Institute, Affiliated Aoyang Hospital ...
Li M, Zhou S, Feng Z, Zhang C
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Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To characterise the metabolic benefits of a GLP‐1/apelin hybrid peptide, namely exendin‐4‐linker‐apelin (ELA), and associated acylated forms, including ELA‐Lys12(γGluPal), ELA‐Lys27(γGluPal) and ELA‐Lys38(γGluPal). Methods Concentration‐ and receptor‐dependent effects of the peptides on insulin secretion and beta‐cell turnover were ...
Ananyaa Sridhar +5 more
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang +5 more
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Cardiovascular diseases (CVD) are the leading cause of death worldwide, with excess visceral adipose tissue (VAT) being identified as an independent indicator of poor cardiovascular outcomes. We examined the association between three indices of VAT, namely, metabolic score for visceral fat (METS‐VF), visceral adiposity index (VAI), and ...
A‐Ra Cho +3 more
wiley +1 more source
Coexisting Asthma and Diabetes Are Associated With Adverse Metabolic and Inflammatory Profiles
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Asthma and diabetes frequently co‐occur and share metabolic and inflammatory features, yet the cardiometabolic profile associated with their coexistence is not well defined. We examined differences in cardiometabolic and inflammatory biomarkers by joint asthma–diabetes status in U.S.
Sixtus Aguree +4 more
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang +7 more
wiley +1 more source
Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler +4 more
wiley +1 more source