Results 11 to 20 of about 28,208 (288)
Annales d'Endocrinologie, 2016 Adipose tissue is now widely recognized as "an organ" able to synthesize and secrete hundred factors collectively called adipokines. These secreted molecules exert pleiotropic actions, notably on the regulation of glucose and lipid metabolism, inflammation, reproduction, or angiogenesis.
Fève, Bruno +4 more
openaire +3 more sources
Cancer Discovery, 2021 Clear cell renal cell carcinoma (ccRCC) is characterized by accumulation of neutral lipids and adipogenic trans-differentiation. We assessed adipokine expression in ccRCC and found that tumor tissues and patient plasma exhibit obesity-dependent ...
S. K. Tan +12 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Obesity and its associated Metabolic Syndromes (Mets) represent a global epidemic health problem. Metabolic inflammation, lipid accumulation and insulin resistance contribute to the progression of these diseases, thereby becoming targets for drug ...
Mengyu Dai +5 more
doaj +1 more source
Changes in adipokine levels and metabolic profiles following bariatric surgery
BMC Endocrine Disorders, 2022 Background Bariatric surgery is considered to be the most effective treatment option for weight reduction in obese patients. Abdominal obesity is frequently accompanied by metabolic syndrome (MS).
Natalja Šebunova +9 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2022 BackgroundOsteoporosis is a multifactorial disorder and a number of genetic variants or loci responsible for bone mineral density (BMD) have been identified.
Sundus Tariq +5 more
doaj +1 more source
A brief overview about the adipokine: Isthmin-1
Frontiers in Cardiovascular Medicine, 2022 Isthmin-1 is a secreted protein with multiple capability; however, it truly attracts our attention since the definition as an adipokine in 2021, which exerts indispensable roles in various pathophysiological processes through the endocrine or autocrine ...
Min Hu +4 more
semanticscholar +1 more source
BIOCHEMICAL PATHWAYS OF METABOLIC DISORDERS IN PSORIASIS
Juvenis Scientia, 2021 The development of metabolic disorders occurs in psoriasis: insulin resistance, systemic inflammation, atherosclerosis, oxidative stress and obesity. The paper presents pathological biochemical pathways of metabolic disorders development which is caused ...
O. V. Samburskaya +2 more
doaj +1 more source
LRG1 is an adipokine that mediates obesity-induced hepatosteatosis and insulin resistance.
Journal of Clinical Investigation, 2021 Dysregulation in adipokine biosynthesis and function contributes to obesity-induced metabolic diseases. However, the identities and functions of many of the obesity-induced secretory molecules remain unknown. Here, we report the identification of leucine-
Sijia He +18 more
semanticscholar +1 more source
Novel adipokine asprosin modulates browning and adipogenesis in white adipose tissue
Journal of Endocrinology, 2021 Obesity is an increasingly serious epidemic worldwide characterized by an increase in the number and size of adipocytes. Adipose tissue maintains the balance between lipid storage and energy utilization.
Yanli Miao +4 more
semanticscholar +1 more source
Exercise in the cold causes greater irisin release but may not be enough for adropin
Chinese Journal of Physiology, 2021 When irisin and adropin were discovered, it was popularly hoped that they would become therapies for metabolic disorders that threaten global health. However, contradictory results have been reported in the subsequent period.
Suleyman Ulupinar +5 more
doaj +1 more source