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Metabolic effects of antidiabetic drugs on adipocytes and adipokine expression
Journal of Cellular Physiology, 2019Several classes of antidiabetic agents have been developed that achieve their hypoglycemic outcomes via various molecular mechanisms. Adipose tissue is a major metabolic and energy‐storing tissue and plays an important role in many metabolic pathways ...
Habib Yaribeygi +3 more
semanticscholar +1 more source
Circulation, 2018
Background: Obesity plays crucial roles in the development of cardiovascular diseases. However, the mechanisms that link obesity and cardiovascular diseases remain elusive.
Yingbao Wang +20 more
semanticscholar +1 more source
Background: Obesity plays crucial roles in the development of cardiovascular diseases. However, the mechanisms that link obesity and cardiovascular diseases remain elusive.
Yingbao Wang +20 more
semanticscholar +1 more source
Adipokines in gestational diabetes
The Lancet Diabetes & Endocrinology, 2014Gestational diabetes is characterised by glucose intolerance with onset or first recognition during pregnancy. The disease shows facets of the metabolic syndrome including obesity, insulin resistance, and dyslipidaemia. Adipokines are a group of proteins secreted from adipocytes, which are dysregulated in obesity and contribute to metabolic and ...
Mathias, Fasshauer +2 more
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Adipokines in human reproduction
Hormone Molecular Biology and Clinical Investigation, 2015Abstract Adipose tissue communicates with other central and peripheral organs by the synthesis and release of substances called adipokines. The most studied adipokine is leptin but others have been recently identified including resistin, adiponectin, chemerin, omentin and visfatin. These adipokines have a critical role in the development
Dupont, Joëlle +4 more
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Comprehensive Physiology, 2017
ABSTRACTOur understanding of adipose tissue as an endocrine organ has been transformed over the last 20 years. During this time, a number of adipocyte‐derived factors or adipokines have been identified. This article will review evidence for how adipokines acting via the central nervous system (CNS) regulate normal physiology and disease pathology.
Craig, Beall +2 more
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ABSTRACTOur understanding of adipose tissue as an endocrine organ has been transformed over the last 20 years. During this time, a number of adipocyte‐derived factors or adipokines have been identified. This article will review evidence for how adipokines acting via the central nervous system (CNS) regulate normal physiology and disease pathology.
Craig, Beall +2 more
openaire +2 more sources
Journal of Renal Nutrition, 2012
The adipose tissue has pleiotropic functions far beyond the mere storage of energy, and it secretes a number of hormones and cytokines, called adipokines, which have biological effects that impact heath and disease. Adipokines are markedly elevated in the plasma of uremic patients, mainly due to decreased renal excretion.
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The adipose tissue has pleiotropic functions far beyond the mere storage of energy, and it secretes a number of hormones and cytokines, called adipokines, which have biological effects that impact heath and disease. Adipokines are markedly elevated in the plasma of uremic patients, mainly due to decreased renal excretion.
openaire +2 more sources
Pregnancy-induced hypertension, preterm birth, and cord blood adipokine levels
European Journal of Pediatrics, 2020E. S. Magalhães +5 more
semanticscholar +1 more source