Results 191 to 200 of about 75,945 (288)

Obesity and cancer: Relevance of DNA damage response. [PDF]

Transl Oncol
Deshmukh B, Ajay AK, Bhat MK.
europepmc   +1 more source

Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

Advanced Biology, Volume 10, Issue 2, February 2026.
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck, Jeroen Bugter, Gizem Yorukoglu, Mina Kazemzadeh Dastjerd, Thomas E. Winkler   +4 more
wiley   +1 more source

Editorial for the Special Issue: Recent Advances in Adipokines-2nd Edition. [PDF]

Biomedicines
Buechler C.
europepmc   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Adipokines and adiposity indices as predictors of glycemic status, insulin resistance, and metabolic dysfunction-associated steatotic liver disease in apparently healthy adults. [PDF]

Medicine (Baltimore)
Mahmood T, Arkawazi L, Salih M, Abdulateef DS.   +3 more
europepmc   +1 more source

Distinct alterations of adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) link dysmetabolism with cognitive decline across the Alzheimer's disease spectrum

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Metabolic disorders are risk factors for Alzheimer's disease (AD), although underlying mechanisms remain unclear. We investigated the relationship between peripheral metabolic markers – adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) – and AD.
Caroline Dallaire‐Théroux, Helena L. Denis, Rosalie Cottez, Cyntia Tremblay, Amélie Provencher, Josue Valentin‐Escalera, Manon Leclerc, Andreanne Loiselle, Marine Tournissac, Olivier Potvin, Sylvie Belleville, Anne Gangloff, Frederic Picard, Henrik Zetterberg, Consortium for the Early Identification of Alzheimer's Disease – Quebec (CIMA‐Q), Frédéric Calon   +15 more
wiley   +1 more source

Phenotype-specific associations of circulating adipokine levels with carotid atherosclerosis: a systematic review and meta-analysis. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Yang S, Shen H, You Y, Fu Z, Guo S, Zhang Y, Liu Q, Yang Y, Li Y, Qin J, Liu P.   +10 more
europepmc   +1 more source

Modulating the Gut Microbiome as a Therapeutic Approach in Multiple Sclerosis: Implications for Gut‐Brain Interactions and Immune Pathways: A Narrative Review

Brain and Behavior, Volume 16, Issue 2, February 2026.
The gut microbiome in multiple sclerosis (MS) shows consistent depletion of short‐chain fatty acid (SCFA)‐producing bacteria, expansion of pro‐inflammatory species, and reduced levels of butyrate, propionate, and indole metabolites. These alterations increase intestinal permeability, disrupt immune balance, and contribute to blood–brain barrier ...
Husna Irfan Thalib, Nuha Fatima, Faaleha Heba Fakruddin, Hosna Hamidullah Ali, Sariya Khan, Mohammed Talha Mohammed Zubair, Mable Pereira, Fatma E. Sayed Hassan   +7 more
wiley   +1 more source

Organokine-Mediated Crosstalk: A Systems Biology Perspective on the Pathogenesis of MASLD-A Narrative Review. [PDF]

Int J Mol Sci
Maria Barbalho S, Laurindo LF, Valenti VE, Méndez-Sánchez N, Ramírez-Mejía MM, Goulart RA.   +5 more
europepmc   +1 more source

WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism [PDF]

, 2020
Abe, T., Furuya, K., Higami, Y., Hoshino, S., Kawabe, H., Kobayashi, M., Konno, R., Miura, K., Mizunoe, Y., Nakagawa, Y., Nakamura, T., Okita, N., Sudo, Y., Tagawa, R., Wakasawa, H.   +14 more
core   +1 more source