Comparative analysis of adipokinetic hormones and their receptors in Blattodea reveals novel patterns of gene evolution [PDF]
Insect Molecular Biology, Volume 32, Issue 6, Page 615-633, December 2023., 2023 Adipokinetic hormone (AKH) is a neuropeptide produced in the insect corpora cardiaca that plays an essential role in mobilising carbohydrates and lipids from the fat body to the haemolymph.
Gäde, Gerd +6 more
core +2 more sources
European Journal of Entomology, 2010 In the present study the hypothesis that there is a feedback between juvenile hormone and adipokinetic hormones (AKHs) was investigated by topical application of the juvenoid methoprene on 9-day-old adult males of the firebug Pyrrhocoris apterus.
Dalibor KODRÍK +2 more
doaj +3 more sources
Gustatory perception and fat body energy metabolism are jointly affected by vitellogenin and juvenile hormone in honey bees. [PDF]
PLoS Genetics, 2012 Honey bees (Apis mellifera) provide a system for studying social and food-related behavior. A caste of workers performs age-related tasks: young bees (nurses) usually feed the brood and other adult bees inside the nest, while older bees (foragers) forage
Ying Wang +3 more
doaj +7 more sources
Five Neuropeptide Ligands Meet One Receptor: How Does This Tally? A Structure-Activity Relationship Study Using Adipokinetic Bioassays With the Sphingid Moth, Hippotion eson [PDF]
Frontiers in Endocrinology, 2019 Adipokinetic hormones (AKHs) play a major role in mobilizing stored energy metabolites during energetic demand in insects. We showed previously (i) the sphingid moth Hippotion eson synthesizes the highest number of AKHs ever recorded, viz.
Heather G. Marco, Gerd Gäde
doaj +3 more sources
A Cold Stress-Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor. [PDF]
Adv Sci (Weinh)Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Zhou J +14 more
europepmc +2 more sources
A South African Scenario: Structure and Function of Peptides of the Adipokinetic Hormone Family of the Brown Locust, Locustana pardalina, and the Putative Role of These Peptides in Plague Management. [PDF]
Arch Insect Biochem Physiol1. The brown locust produces the three adipokinetic hormones Locmi‐AKH‐I, ‐II and ‐III found also in the migratory locust. 2. Flight is characterised by differential changes in haemolymph carbohydrate and lipid levels. 3. Modelling ligand‐receptor binding is proposed as important step to a new strategy to combat the brown locust.
Gäde G, Marco HG.
europepmc +2 more sources
Homeostatic Counter-Regulation Mediates Spermidine-Induced Triacylglyceride Reduction in Drosophila melanogaster-From Phenotype to Molecular Mechanism. [PDF]
FASEB JIn Drosophila melanogaster females fed a standard diet containing 2.5% yeast extract (low‐yeast diet), spermidine (Spd) administration does not enhance the endogenous Spd pool but increases the excretion of catabolic N1‐acetylspermidine (N1AcSpd) and reduces fat stores. This process requires the catabolic Akh/AkhR pathway.
Lüersen K +6 more
europepmc +2 more sources
Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan-PKCα-AKH/AKHR Signaling in Pear Psyllid Morph Transition. [PDF]
Adv Sci (Weinh)At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Li J +6 more
europepmc +2 more sources
Structural Diversity of Adipokinetic Hormones in the Coleopteran Suborder Polyphaga (Excluding Cucujiformia). [PDF]
Arch Insect Biochem PhysiolAdipokinetic hormones of Polyphaga beetles (minus Cucujiformia series) were sequenced and confirmed via mass spectrometry. Schgr‐AKH‐II is assumed as ancestral AKH in Coleoptera. Radiation of AKH diversity during the evolution of Scarabaeoidea. ABSTRACT Beetles are the largest animal group, in general.
Gäde G, König S, Marco HG.
europepmc +2 more sources
Frontiers in Physiology, 2021 Metabolism, growth, and development are intrinsically linked, and their coordination is dependent upon inter-organ communication mediated by anabolic, catabolic, and steroid hormones.
Bryon N. Hughson +2 more
doaj +1 more source