Results 111 to 120 of about 157,661 (308)

Role of arginase 2 in systemic metabolic activity and adipose tissue fatty acid metabolism in diet-induced obese mice [PDF]

open access: yes, 2019
Visceral adipose tissue (VAT) inflammation and metabolic dysregulation are key components of obesity-induced metabolic disease. Upregulated arginase, a ureahydrolase enzyme with two isoforms (A1-cytosolic and A2-mitochondrial), is implicated in ...
Atawia, Reem T   +8 more
core   +2 more sources

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

open access: yesFood Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu   +12 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti   +2 more
wiley   +1 more source

Adiponectin: A Predictor for Breast Cancer Survival?

open access: yesEuropean Journal of Breast Health, 2019
Objective:Breast cancers in women with low serum adiponectin levels have been reported to show phenotypes that are more aggressive. In 2008, we investigated the relationship between serum adiponectin levels and breast cancer in our case-controlled study ...
Hikmet Erhan Güven   +3 more
doaj   +1 more source

Total and high-molecular-weight adiponectin levels in relation to insulin resistance among overweight/obese adults

open access: yesCentral Asian Journal of Global Health, 2013
Objective: To determine whether baseline levels or intervention-associated changes in total and high molecular weight (HMW) adiponectin levels were associated with insulin resistance after six months of behavioral treatment for weight loss.
Sushama D. Acharya   +4 more
doaj   +1 more source

Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta-Analysis. [PDF]

open access: yesObes Sci Pract
ABSTRACT Background Adipokines are dysregulated in obesity and exacerbate proinflammatory conditions. Although several studies have investigated adipokine levels in obesity, their findings have been inconsistent, leaving the precise nature of these alterations uncertain.
Sunita S   +10 more
europepmc   +2 more sources

T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity. [PDF]

open access: yes, 2017
BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function.
Ambrosio, Anastasia   +7 more
core   +2 more sources

Hyperlipidemic plasma molecules bind and inhibit adiponectin activity [PDF]

open access: gold, 2022
Yanqing Zhang   +8 more
openalex   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

open access: yesFood Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra   +2 more
wiley   +1 more source

Mediating effect of adiponectin between free fatty acid and tumor necrosis factor-α in patients with diabetes

open access: yesNutrition & Diabetes
Background/Objectives Increased free fatty acid (FFA) promotes adiponectin secretion in healthy subjects and induces inflammation in diabetes. Given the potential pro-inflammatory role of adiponectin in “adiponectin paradox”, we performed this study in ...
Zhang Xia   +9 more
doaj   +1 more source

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