Results 31 to 40 of about 157,661 (308)

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Plasma omentin levels are inversely associated with atherosclerosis in type 2 diabetes patients with increased plasma adiponectin levels: a cross-sectional study

open access: yesCardiovascular Diabetology, 2019
Background Omentin and adiponectin are among the anti-inflammatory and anti-atherogenic adipokines that have potentially beneficial effects on cardiovascular disorders.
Masami Nishimura   +11 more
doaj   +1 more source

Exploring the Relationship between Plasma Adiponectin, Gender, and Underlying Diseases in Severe Illness

open access: yesBiomedicines, 2023
Adiponectin is low in obesity, plays a crucial role in metabolic health, and, moreover, possesses immunoregulatory properties. However, studies examining its levels in patients with systemic inflammatory response syndrome (SIRS) or sepsis have yielded ...
Patricia Mester   +5 more
doaj   +1 more source

Adiponectin protects against paraquat-induced lung injury by attenuating oxidative/nitrative stress. [PDF]

open access: yes, 2014
The specific mechanisms underlying paraquat (PQ)-induced lung injury remain unknown, which limits understanding of its cytotoxic potential. Although oxidative stress has been established as an important mechanism underlying PQ toxicity, multiple ...
Cao, Yu   +9 more
core   +2 more sources

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran   +17 more
wiley   +1 more source

Total and High Molecular Weight Adiponectin Levels and Prediction of Cardiovascular Risk in Diabetic Patients

open access: yesInternational Journal of Endocrinology, 2015
The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM).
Dagmar Horáková   +14 more
doaj   +1 more source

The rab11 effector protein FIP1 regulates adiponectin trafficking and secretion. [PDF]

open access: yesPLoS ONE, 2013
Adiponectin is an adipokine secreted by white adipocytes involved in regulating insulin sensitivity in peripheral tissues. Secretion of adiponectin in adipocytes relies on the endosomal system, however, the intracellular machinery involved in mediating ...
Brian P Carson   +4 more
doaj   +1 more source

Effects of physical exercise on adiponectin, leptin, and inflammatory markers in childhood obesity: systematic review and meta-analysis [PDF]

open access: yes, 2018
Background: New findings on adipose tissue physiology and obesity-Associated inflammation status suggest that modification of the adipokine level can be relevant for the long-Term prevention of obesity-Associated chronic disease. Objectives: The scope of
Bianco, Antonio   +7 more
core   +2 more sources

Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes

open access: yesCardiovascular Diabetology, 2006
Background Systemic adiponectin is reduced in patients with cardiovascular disease (CVD) and low adiponectin may contribute to the pathogenesis of atherosclerosis.
Maier Kevin   +9 more
doaj   +1 more source

Adiponectin Signaling Regulates Lipid Production in Human Sebocytes. [PDF]

open access: yesPLoS ONE, 2017
Adiponectin plays important roles in metabolic function, inflammation and multiple biological activities in various tissues. However, evidence for adiponectin signaling in sebaceous glands is lacking, and its role remains to be clarified.
Yu Ra Jung   +10 more
doaj   +1 more source

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