Results 151 to 160 of about 1,754 (193)

Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis. [PDF]

open access: yesProc Natl Acad Sci U S A
Ozaki MK   +7 more
europepmc   +1 more source

Adipophilin Is a Sensitive Marker for Lipid Loading in Human Blood Monocytes

open access: yesBiochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2001
Adipophilin, a marker of lipid accumulation initially described in adipocytes, was recently shown to be induced in macrophage foam cells. We found that even freshly isolated blood monocytes express adipophilin and that the amount of adipophilin protein is variable in monocytes from different healthy individuals. However, the physiological expression of
Gerd Schmitz   +2 more
exaly   +4 more sources

Novel Prognostication Biomarker Adipophilin Reveals a Metabolic Shift in Uveal Melanoma and New Therapeutic Opportunities

open access: yesJournal of Pathology, 2023
Metastatic uveal melanoma remains incurable at present. We previously demonstrated that loss of BAP1 gene expression in tumour cells triggers molecular mechanisms of immunosuppression in the tumour microenvironment (TME) of metastatic uveal melanoma ...
Sarah Coupland   +2 more
exaly   +2 more sources

Adipophilin: roles in physiology and pathology

Journal of Clinical Pathology, 2022
Adipophilin (ADRP/ADPH/PLIN2), an adipocyte differentiation-related protein, is highly expressed at a very early time during the differentiation of adipocytes. It assists in the formation and maintenance of intracellular lipid droplets and plays a role in regulating the physiological functions of the body.
Feng-Zeng Li, Sheng Fang
openaire   +2 more sources

Perilipin and Adipophilin Expression in Sebaceous Carcinoma and Mimics

Human Pathology, 2013
Although adipophilin has been reported to be a sensitive marker for sebaceous carcinoma, others have noted its expression in squamous cell carcinoma and a variety of noncutaneous tumors, suggesting that lipid droplet accumulation is a frequent feature of neoplastic cells.
Mai P Hoang
exaly   +3 more sources

Adipophilin expression in skin lesions with clear cell histology

Journal of Clinical Pathology, 2021
Aims Clear cells formed due to depositions of glycogen or lipids in the cytoplasm commonly occur in various tissues. Adipophilin (ADP), a lipid regulatory protein, is closely related to lipid droplets. This study aims to examine adipophilin expression in clear cells of various skin lesions.
Feng-Zeng Li   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy