CD47 differentially regulates white and brown fat function
Biology Open, 2020 Mechanisms that enhance energy expenditure are attractive therapeutic targets for obesity. Previously we have demonstrated that mice lacking cd47 are leaner, exhibit increased energy expenditure, and are protected against diet-induced obesity.
Heather Norman-Burgdolf +3 more
doaj +1 more source
Case report: brown fat accumulation of Tc-99m macroaggregated albumin in a lung perfusion study in a patient with multiple lung arteriovenous malformations and right-to-left shunting [PDF]
, 2015 An 18-year-old man was preoperatively assessed for a varicocele and found to be hypoxemic. A Tc-99m macroaggregated albumin lung perfusion scan showed right-to-left shunting, evidenced by increased radiotracer uptake in the brain, kidneys, thyroid gland,
Marashdeh, Wael, Wahl, Richard L
core +2 more sources
3D Printing Strategies for Bioengineering Human Cornea
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan +4 more
wiley +1 more source
Senescent T Cell Induces Brown Adipose Tissue “Whitening” Via Secreting IFN-γ
Frontiers in Cell and Developmental Biology, 2021 Aging-associated chronic inflammation is a key contributing factor to a cluster of chronic metabolic disorders, such as cardiovascular disease, obesity, and type 2 diabetes.
Xiao-Xi Pan +7 more
doaj +1 more source
A percutaneous needle biopsy technique for sampling the supraclavicular brown adipose tissue depot of humans. [PDF]
, 2015 Brown adipose tissue (BAT) has been proposed as a potential target tissue against obesity and its related metabolic complications. Although the molecular and functional characteristics of BAT have been intensively studied in rodents, only a few studies ...
Annamalai, P +6 more
core +2 more sources
Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice
Molecular Metabolism, 2023 Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation and white adipose tissue (WAT) browning.MaR1 actions were tested in cultured murine brown adipocytes and in human mesenchymal stem cells ...
Laura M. Laiglesia +19 more
openaire +7 more sources
Advanced Materials, EarlyView.Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi +8 more
wiley +1 more source
Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Advanced Materials, EarlyView.Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels
Molecular Metabolism, 2021 Objective: Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling protein 1
Subramanian Senthivinayagam +20 more
doaj +1 more source
Characterization of cold-induced remodelling reveals depot-specific differences across and within brown and white adipose tissues in mice [PDF]
, 2016 Brown and beige adipose tissues dissipate energy in the form of heat via mitochondrial uncoupling protein 1, defending against hypothermia and potentially obesity.
Atit +55 more
core +1 more source