Results 111 to 120 of about 77,506 (302)

Activation of classical brown adipocytes in the adult human perirenal depot is highly correlated with PRDM16-EHMT1 complex expression.

PLoS ONE, 2015
Brown fat generates heat to protect against cold and obesity. Adrenergic stimulation activates the thermogenic program of brown adipocytes. Although the bioactivity of brown adipose tissue in adult humans had been assumed to very low, several studies ...
Gaku Nagano, Haruya Ohno, Kenji Oki, Kazuhiro Kobuke, Tsuguka Shiwa, Masayasu Yoneda, Nobuoki Kohno   +6 more
doaj   +1 more source

Three years with adult human brown adipose tissue

, 2010
The presence of active brown adipose tissue in adult humans has been recognized in general physiology only since 2007. The intervening three years established that the depots originally observed by (18)F-fluoro-deoxy-glucose positron emission tomography (
Nedergaard, Jan,, Jan Nedergaard, Bengtsson, Tore,, Tore Bengtsson, Cannon, Barbara,, Barbara Cannon   +5 more
core   +1 more source

Regulation of human brown adipose tissue activity [PDF]

The rising prevalence of obesity globally poses significant morbidity and mortality, as obesity increases the risk of developing a number of diseases such as diabetes, hypertension and cardiovascular disease.
Kwok, T’ng Choong
core   +1 more source

Adipose tissue derived factors in obesity, inflammation & energy homeostasis [PDF]

Obesity is the foremost contributory factor in the progression to type 2 diabetes mellitus (T2DM). Moreover, chronic inflammation, through activation of innate immunity is proposed to link obesity, insulin resistance and T2DM.
Kusminski, C. M.
core  

Brown adipose tissue—a new role in humans?

, 2010
New targets for pharmacological interventions are of great importance to combat the epidemic of obesity. Brown adipose tissue could potentially represent one such target.
Enerbäck, Sven,, Sven Enerbäck, Martin E. Lidell, Lidell, Martin,   +3 more
core   +1 more source

mmunohistochemical Identification And Quantification Of Brown Adipocytes In Human Adipose Tissue.

مجله كليه طب الكندي, 2016
Background: Obesity is a worldwide challenge and is closely connected to many metabolic diseases. Two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT) have been identified.
Insaf Jasim Mahmoud, Insaf Jasim Mahmoud, bdul Hadi Liebi, Faris Abdul Kareem Khazaal   +3 more
doaj  

Inverse association between obesity and intestinal endometriosis: Findings from a cross‐sectional study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates the association between obesity and the presence of bowel endometriosis in patients undergoing surgery. Methods A retrospective cross‐sectional observational study was conducted with patients treated between September 2023 and December 2024, at a specialized endometriosis outpatient clinic of a tertiary hospital ...
Tereza Carolina Fonseca Corrêa, Marco Aurelio Pinho Oliveira   +1 more
wiley   +1 more source

Brown vs. White Adipose Tissue: Brown Adipose Tissue is a Source of Multipoint Stem Cells with Greater Propensity for Neurogenesis [PDF]

, 2016
Spinal cord injuries can lead to life long debilitations, in some cases, paralysis. Patients suffering with spinal cord injury, however, may find hope for improved functionality of debilitated limbs via cell transplantation.
Penton, Ashley Abigail
core  

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease

Experimental Physiology
Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine ...
Anna Malicka, Aysha Ali, Amanda D. V. MacCannell, Lee D. Roberts   +3 more
doaj   +1 more source