Results 131 to 140 of about 171,717 (298)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

White and brown adipose tissue share a convergent fibro-adipogenic progenitor population

EMBO Reports
Adipose tissue heterogeneity has emerged as a central factor in regulating adipose tissue function in physiology and pathophysiology, yet tools to model and study this diversity in vitro remain limited.
Hoang V Bui, Julia K Hansen, Valentina Lo Sardo, Andrea Galmozzi   +3 more
doaj   +1 more source

Sensory nerve and neuropeptide diversity in adipose tissues

Molecules and Cells
: Both brown and white adipose tissues (BAT/WAT) are innervated by the peripheral nervous system, including efferent sympathetic nerves that communicate from the brain/central nervous system out to the tissue, and afferent sensory nerves that communicate
Gargi Mishra, Kristy L. Townsend
doaj   +1 more source

Autologous Extracellular Matrix‐Based Cell‐Free Therapy for Tissue Regeneration Through Trem2+ Macrophages Mediated Angiogenesis

Exploration, EarlyView.
ADF is prepared as a cell‐free bio‐membrane from autologous adipose ECM using simple physical techniques inspired by “papermaking”. It boasts superior properties and facilitates tissue regeneration through Trem2+ macrophages‐mediated angiogenesis. ADF can be stored long‐term for personalized medicine, offering insights into autologous ECM preservation ...
Mengmeng Hou, Nini Shi, Yajie Guo, Jiezhang Tang, Han Peng, Baoyan Liang, Yixuan Yu, Chenggang Yi, Huichen Li   +8 more
wiley   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

High-Intensity Interval Training Reduces Adipocyte Size and enhances the Thermogenic Activity of White and Brown Adipose Tissue in Male Wistar Rats

International Journal of Preventive Medicine
Background: This research aims to investigate and compare the effect of high-intensity interval training on some effective factors in these metabolic diseases and the possibility of signaling thermogenesis and browning in white and brown adipose tissue ...
Ahmad Reza Moein, Mohammad Javad Pourvaghar, Fatemeh Kazeminasab   +2 more
doaj   +1 more source

A Third Variable in Obesity: The Effects of Brown Adipose Tissue on Thermogenesis

, 1981
Approaches to weight management which consider only energy intake and/or expenditure do not consistently lead to favorable outcomes. A third variable, thermogenesis, must also be considered in a comprehensive understanding of obesity· Three types of ...
McMinn, Mark R.
core  

White adipose tissue uptake on 18F FDG PET/CT: A case report

Radiology Case Reports
Three distinct types of adipose tissue have been characterized: brown, white, and beige. Brown adipose tissue (BAT) is typically found in specific regions including the anterior cervical, supraclavicular, axillary, and paravertebral areas.
Maria Andrea Parra Corral, MD, Jesus R. Diaz, MD   +1 more
doaj   +1 more source

Inter-individual variation in gene expression in torpid and interbout euthermic Arctic ground squirrels [PDF]

, 2006
Thesis (M.S.) University of Alaska Fairbanks, 2006Alaskan Arctic ground squirrels, Spermophilus paryii, hibernate about seven months per year. During two-week torpor periods, respiration, circulation, metabolism, and catabolism are dramatically decreased,
Burman, Adlai Max
core