Results 171 to 180 of about 168,667 (304)

Functional Complexity of Thermogenic Adipose Tissue: From Thermogenesis to Metabolic and Fibroinflammatory Crosstalk. [PDF]

Int J Mol Sci
Jalloul W, Grierosu IC, Jalloul D, Stefanescu C, Ghizdovat V.   +4 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

Glucose sensing and homeostasis by adipocyte GPCR. [PDF]

Front Endocrinol (Lausanne)
Hasan N, Chhabra KH.
europepmc   +1 more source

Brown adipose tissue in humans [PDF]

Proceedings of the Nutrition Society, 1989
openaire   +3 more sources

Measuring Peripheral Tissue DHA Turnover Using a Novel 13C Enrichment Technique

Lipids, EarlyView.
ABSTRACT Recently, through the use of compound‐specific isotope analysis (CSIA), our lab validated the utility of 13C enrichment (δ13C) of docosahexaenoic acid (DHA) by using a very high δ13C in a diet switch study by measuring brain, liver, and plasma DHA turnover and half‐lives via high‐precision gas chromatography combustion isotope ratio mass ...
Brinley J. Klievik, Adam H. Metherel, Rodrigo Valenzuela, Richard P. Bazinet   +3 more
wiley   +1 more source

Cetacean loss of the master adipose tissue regulator β₃-adrenergic receptor may underlie their thick blubber and an Oligocene radiation and dispersal. [PDF]

Nat Commun
Tian R, Zhang T, Dong H, Seim I, Yang G.
europepmc   +1 more source

Mesenchymal Stem Cell‐Engrafted Bacterial Cellulose and Graphene Oxide Scaffolds Enhance Peripheral Nerve Repair in a Rat Model

Macromolecular Materials and Engineering, EarlyView.
This study investigates the use of graphene oxide‐decorated bacterial cellulose (BC/GO) scaffolds combined with mesenchymal stem cells (MSCs) to enhance axonal regeneration after sciatic nerve injury in rats. Graphene oxide is embedded monodispersely into the BC fibrillar matrix.
Ismail Simsek, Semra Unal, Efecan Cekic, Ecem Dogan, Ozlem Kirazli, Ferhat Harman   +5 more
wiley   +1 more source

Fatty acid composition of lipid fractions in white- and brown-like adipocytes derived from human mesenchymal stem cells. [PDF]

Adipocyte
Abbasi K, Mehdizadeh A, Hamishehkar H, Nouri M, Darabi M.   +4 more
europepmc   +1 more source

Preserved Thermoregulation in Huntington's Disease: Insights from an Observational Case–Control Study

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Thermoregulation is critical for preventing hyperthermia during physical activity. In Huntington's disease (HD), research on possible thermoregulatory alterations has received little attention. Objectives We aimed to investigate and compare skin temperature differences before and after exercise between HD patients and healthy ...
Lucía Simón‐Vicente, Jéssica Rivadeneyra‐Posadas, María Soto‐Célix, Javier Raya‐González, Alejandro Rodríguez‐Fernández, Daniel Castillo‐Alvira, Fernando Vázquez, Esther Cubo   +7 more
wiley   +1 more source