Results 21 to 30 of about 347,415 (326)

An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

Reviews in Endocrine & Metabolic Disorders, 2023
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT primarily stores energy, BAT dissipates energy as heat for thermoregulation.
Zeinab Ghesmati, Mohsen Rashid, S. Fayezi, F. Gieseler, E. Alizadeh, Masoud Darabi   +5 more
semanticscholar   +1 more source

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

Frontiers in Endocrinology, 2023
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy expenditure, has been extensively studied as a potential avenue to combat obesity.
K. Ziqubu, P. Dludla, S. Mthembu, B. Nkambule, S. Mabhida, B. Jack, T. M. Nyambuya, S. Mazibuko-Mbeje   +7 more
semanticscholar   +1 more source

Brown Adipose Tissue—A Translational Perspective

Endocrine reviews, 2022
Brown adipose tissue (BAT) displays the unique capacity to generate heat through uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for cardiometabolic diseases.
A. Carpentier, D. Blondin, F. Haman, D. Richard   +3 more
semanticscholar   +1 more source

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

Adipocyte, 2021
Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng, Jingkang Wang, Hongyu Dai, Yuhui Duan, Yongcheng An, Lu Shi, Yinglan Lv, Huimin Li, Chen Wang, Quantao Ma, Yaqi Li, Pengfei Li, Haifeng Du, Baosheng Zhao   +13 more
semanticscholar   +1 more source

Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis

Nature Communications, 2021
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network.
Anna Whitehead, Fynn N. Krause, Amy Moran, Amanda Maccannell, J. Scragg, Ben D. McNally, E. Boateng, Steven A. Murfitt, S. Virtue, John Wright, J. Garnham, G. Davies, J. Dodgson, J. Schneider, A. Murray, C. Church, A. Vidal-Puig, K. Witte, J. Griffin, L. Roberts   +19 more
semanticscholar   +1 more source

Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis

International Journal of Molecular Sciences, 2021
The increased worldwide prevalence of obesity, insulin resistance, and their related metabolic complications have prompted the scientific world to search for new possibilities to combat obesity.
K. Maliszewska, A. Krętowski
semanticscholar   +1 more source

Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue

Frontiers in Endocrinology, 2020
Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann, Sebastian Dieckmann, Sebastian Dieckmann, Stefanie Maurer, Stefanie Maurer, Stefanie Maurer, Tobias Fromme, Tobias Fromme, Tobias Fromme, Cécilia Colson, Kirsi A. Virtanen, Ez-Zoubir Amri, Martin Klingenspor, Martin Klingenspor, Martin Klingenspor   +14 more
doaj   +1 more source

Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue. [PDF]

Chin Med
Background Obesity has become a critical public health challenge worldwide. Prioritizing prevention and tackling root causes—rather than merely managing symptoms—is critical to curbing this pandemic.
Huang Z, Zhao Z, Shi H, He R, Feng Q, Geng Y, Zhang L, Zhang T, Yan Z, Jia Z, Jiang Y, Sun J, Cai A, Dong S, Yang L.   +14 more
europepmc   +2 more sources

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit [PDF]

, 2013
Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue.
Chen, Y., Froehlich, H., Haas, B., Kipschull, S., Meister, G., Pfeifer, A., Siegel, F.   +6 more
core   +1 more source

Identification and importance of brown adipose tissue in adult humans.

New England Journal of Medicine, 2009
BACKGROUND Obesity results from an imbalance between energy intake and expenditure. In rodents and newborn humans, brown adipose tissue helps regulate energy expenditure by thermogenesis mediated by the expression of uncoupling protein 1 (UCP1), but ...
A. Cypess, S. Lehman, Gethin Williams, Ilan Tal, D. Rodman, A. Goldfine, F. Kuo, E. Palmer, Y. Tseng, A. Doria, G. Kolodny, R. Kahn   +11 more
semanticscholar   +1 more source