Results 21 to 30 of about 359,090 (346)

Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis

International Journal of Molecular Sciences, 2021
The increased worldwide prevalence of obesity, insulin resistance, and their related metabolic complications have prompted the scientific world to search for new possibilities to combat obesity.
K. Maliszewska, A. Krętowski
semanticscholar   +1 more source

Energy metabolism in brown adipose tissue

The FEBS Journal, 2021
Brown adipose tissue (BAT) is well known to burn calories through uncoupled respiration, producing heat to maintain body temperature. This ‘calorie wasting’ feature makes BAT a special tissue, which can function as an ‘energy sink’ in mammals.
Zhichao Wang, Qiong A. Wang, Yong Liu, Lei Jiang   +3 more
semanticscholar   +1 more source

Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning

International Journal of Molecular Sciences, 2022
The present narrative review gathers the studies reported so far, addressing sex differences in the effects of cold exposure, feeding pattern and age on brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning. In rodents, when exposed to decreasing temperatures, females activate thermogenesis earlier. Results obtained in humans
Iker Gómez-García, Jenifer Trepiana, Alfredo Fernández-Quintela, Marta Giralt, María P. Portillo   +4 more
openaire   +5 more sources

Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue

Frontiers in Endocrinology, 2020
Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann, Sebastian Dieckmann, Sebastian Dieckmann, Stefanie Maurer, Stefanie Maurer, Stefanie Maurer, Tobias Fromme, Tobias Fromme, Tobias Fromme, Cécilia Colson, Kirsi A. Virtanen, Ez-Zoubir Amri, Martin Klingenspor, Martin Klingenspor, Martin Klingenspor   +14 more
doaj   +1 more source

Intravitreally injected anti-VEGF antibody reduces brown fat in neonatal mice [PDF]

, 2015
Anti-vascular endothelial growth factor (VEGF) agents are the mainstay treatment for various angiogenesis-related retinal diseases. Currently, bevacizumab, a recombinant humanized anti-VEGF antibody, is trailed in retinopathy of prematurity, a ...
A Hellstrom, AL Hard, AM Cypess, B Cannon, BJ Lee, Chang Sik Cho, D Lepore, DF Martin, DH Jo, Dong Hyun Jo, H Kim, HA Mintz-Hittner, HA Mintz-Hittner, HK Sung, I Elias, I Shimizu, J Qian, Jeong Hun Kim, JH Kim, Jin Hyoung Kim, K Sun, L Sidossis, LA Kim, LE Smith, M Bagchi, M Tolentino, Marcus Fruttiger, Marià Alemany, MB Powner, Michael B. Powner, MO Stefanini, MS Gordon, P van Wijngaarden, RL Avery, RL Avery, Sung Wook Park, T Miyake, T Sato, WC Wu, Y Cao, Y Xue   +40 more
core   +12 more sources

Brown adipose tissue and bone [PDF]

International Journal of Obesity Supplements, 2015
Brown adipose tissue (BAT) is capable of transforming chemically stored energy, in the form of triglycerides, into heat. Recent studies have shown that metabolically active BAT is present in a large proportion of adult humans, where its activity correlates with a favorable metabolic status. Hence, the tissue is now regarded as an interesting target for
S Enerbäck, Martin E. Lidell
openaire   +3 more sources

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit [PDF]

, 2013
Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue.
Chen, Y., Froehlich, H., Haas, B., Kipschull, S., Meister, G., Pfeifer, A., Siegel, F.   +6 more
core   +1 more source

The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity

Nature Communications, 2020
Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provides ...
Marion Peyrou, Rubén Cereijo, Tania Quesada-López, Laura Campderrós, Aleix Gavaldà-Navarro, Laura Liñares-Pose, Elena Kaschina, Thomas Unger, Miguel López, Marta Giralt, Francesc Villarroya   +10 more
doaj   +1 more source

METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice

Nature Communications, 2020
Brown adipose tissue (BAT) undergoes rapid postnatal development and then protects against cold and obesity into adulthood. However, the molecular mechanism that determines postnatal development and maturation of BAT is largely unknown. Here we show that
Yuqin Wang, Ming Gao, Fuxing Zhu, Xinzhi Li, Ying Yang, Qiuxin Yan, Linna Jia, Liwei Xie, Zheng Chen   +8 more
semanticscholar   +1 more source

Multiple regulatory steps are involved in the control of lipoprotein lipase activity in brown adipose tissue.

Journal of Lipid Research, 1996
Lipoprotein lipase (LPL) supplies brown adipose tissue with fatty acids for nonshivering thermogenesis. In brown adipose tissue of the Djungarian hamster we studied i) the molecular mechanisms involved in cold-induced stimulation of LPL activity, ii) the
M Klingenspor, C Ebbinghaus, G Hülshorst, S Stöhr, F Spiegelhalter, K Haas, G Heldmaier   +6 more
doaj   +1 more source