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Deciphering White Adipose Tissue Heterogeneity [PDF]
Biology, 2019 Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body.
Quyen Luong, Jun Huang, Kevin Y. Lee
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High-Intensity Interval Training Reduces Adipocyte Size and enhances the Thermogenic Activity of White and Brown Adipose Tissue in Male Wistar Rats [PDF]
International Journal of Preventive MedicineBackground: This research aims to investigate and compare the effect of high-intensity interval training on some effective factors in these metabolic diseases and the possibility of signaling thermogenesis and browning in white and brown adipose tissue ...
Ahmad Reza Moein +2 more
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Neuroimmune regulation of white adipose tissues [PDF]
The FEBS Journal, 2021 The white adipose tissues (WAT) are located in distinct depots throughout the body. They serve as an energy reserve, providing fatty acids for other tissues via lipolysis when needed, and function as an endocrine organ to regulate systemic metabolism. Their activities are coordinated through intercellular communications among adipocytes and other cell ...
Xinmin Qian +3 more
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Biology of Sex Differences, 2022 Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2.
Jacob E. Pruett +9 more
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Nutrition & Metabolism, 2022 Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado +6 more
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Dynamic changes in the transcriptome of tRNA-derived small RNAs related with fat metabolism
Scientific Data, 2023 The prevalence of obesity and overweight is steadily rising, posing a significant global challenge for humanity. The fundamental cause of obesity and overweight lies in the abnormal accumulation of adipose tissue.
Tianci Liao +6 more
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Effects of a Phosphodiesterase inhibitor on the Browning of Adipose Tissue in Mice
Biomedicines, 2022 Cilostazol is a selective inhibitor of phosphodiesterase type 3 (PDE3) that increases intracellular cyclic adenosine monophosphate (cAMP), which plays a critical role in the development of the beige phenotype and the activation of its thermogenic program
Da Hea Seo +6 more
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The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least [PDF]
Endocrinology and Metabolism, 2023 The growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for
Juan Cai, Fenfen Wang, Mengle Shao
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Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
Frontiers in Endocrinology, 2020 Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann +14 more
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AdipoAtlas: A reference lipidome for human white adipose tissue
Cell Reports Medicine, 2021 Summary: Obesity, characterized by expansion and metabolic dysregulation of white adipose tissue (WAT), has reached pandemic proportions and acts as a primer for a wide range of metabolic disorders.
Mike Lange +6 more
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