Molecular mechanisms regulating perivascular adipose tissue - potential pharmacological targets? [PDF]
No abstract ...
Kennedy, Simon, Salt, Ian P.
core +1 more source
Fetal development of subcutaneous white adipose tissue is dependent on Zfp423
Objective: Zfp423 is a multi zinc-finger transcription factor expressed in preadipocytes and mature adipocytes in vivo. Our recent work has revealed a critical role for Zfp423 in maintaining the fate of white adipocytes in adult mice through suppression ...
Mengle Shao +5 more
doaj +1 more source
Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C. +12 more
core +1 more source
A percutaneous needle biopsy technique for sampling the supraclavicular brown adipose tissue depot of humans. [PDF]
Brown adipose tissue (BAT) has been proposed as a potential target tissue against obesity and its related metabolic complications. Although the molecular and functional characteristics of BAT have been intensively studied in rodents, only a few studies ...
Annamalai, P +6 more
core +2 more sources
Impact of white adipose tissue in AD pathology
Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
Bettinetti-Luque, Miriam +7 more
openaire +2 more sources
Mitochondrial function/dysfunction in white adipose tissue
New Findings What is the topic of this review?The review covers basic knowledge about the role of mitochondria in the homeostatic function of adipose tissue. It also provide a comprehensive analysis of how mitochondrial function is affected during obesity and lipoatrophies and discuss the results of recent studies that targeted mitochondrial function ...
Sihem Boudina, Timothy E. Graham
openaire +3 more sources
Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]
Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G. +13 more
core +1 more source
As one of the main pathogenic factors of cardiovascular and cerebrovascular diseases, the incidence of metabolic diseases such as adiposity and metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing annually.
Dihong Gong +8 more
doaj +1 more source
Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches? [PDF]
Heart disease is a major cause of morbidity and mortality throughout the world. Some cardiovascular conditions can be modulated by lifestyle factors such as increased exercise or a healthier diet, but many require surgical or pharmacological ...
Agra +164 more
core +1 more source
Relationships between rodent white adipose fat pads and human white adipose fat depots
The objective of this review was to compare and contrast the physiological and metabolic profiles of rodent white adipose fat pads with white adipose fat depots in humans.
Daniella E. Chusyd +3 more
doaj +1 more source

