Results 101 to 110 of about 492,704 (351)
The Mechanism of White and Brown Adipocyte Differentiation [PDF]
Diabetes & Metabolism Journal, 2013 Obesity gives vent to many diseases such as type 2 diabetes, hypertension, and hyperlipidemia, being considered as the main causes of mortality and morbidity worldwide.
Hironori Nakagami
doaj +1 more source
Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes
Journal of physiology and biochemistry, 2018 Mammalian adipose tissue is traditionally categorized into white and brown relating to their function and morphology: while white serves as an energy storage, brown adipose tissue acts as the heat generator maintaining the core body temperature. The most
A. Kaisanlahti, Tumo Glumoff
semanticscholar +1 more source
, 2012 Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure,
Townsend, Kristy L, Tseng, Yu-Hua
core +1 more source
Advanced Healthcare Materials, EarlyView.This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin +14 more
wiley +1 more source
EGCG Reduces Obesity and White Adipose Tissue Gain Partly Through AMPK Activation in Mice
Frontiers in Pharmacology, 2018 (-)-Epigallocatechin-3-gallate (EGCG), which is the most abundant catechin in green tea, has many potential health benefits, including decreased weight gain and/or adipose tissue weight. Suggested mechanisms for body weight reduction by EGCG include: (1)
Fang Li +8 more
semanticscholar +1 more source
Mitochondrial function/dysfunction in white adipose tissue
Experimental Physiology, 2014 New Findings What is the topic of this review?The review covers basic knowledge about the role of mitochondria in the homeostatic function of adipose tissue. It also provide a comprehensive analysis of how mitochondrial function is affected during obesity and lipoatrophies and discuss the results of recent studies that targeted mitochondrial function ...
Sihem, Boudina, Timothy E, Graham
openaire +2 more sources
Imaging White Adipose Tissue with Confocal Microscopy [PDF]
, 2014 Adipose tissue is composed of a variety of cell types that include mature adipocytes, endothelial cells, fibroblasts, adipocyte progenitors, and a range of inflammatory leukocytes. These cells work in concert to promote nutrient storage in adipose tissue depots and vary widely based on location. In addition, overnutrition and obesity impart significant
Gabriel, Martinez-Santibañez +2 more
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White adipose tissue coloring by intermittent fasting [PDF]
Cell Research, 2017 Intermittent fasting (IF) has been shown to promote metabolic health in several organisms. Two recent papers show that IF induces white adipose tissue beiging and increases thermogenesis, which improves metabolic health in mice.
Alitalo Kari +3 more
openaire +2 more sources
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses
Advanced Healthcare Materials, EarlyView.Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri +6 more
wiley +1 more source
Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation [PDF]
Diabetes & Metabolism Journal, 2019 Adipose tissue inflammation is considered a major contributing factor in the development of obesity-associated insulin resistance and cardiovascular diseases. However, the cause of adipose tissue inflammation is presently unclear.
Chang-Yun Woo +4 more
doaj +1 more source