Objective: Sulfonylureas (SUs) are still among the mostly prescribed antidiabetic drugs with an established mode of action: release of insulin from pancreatic β-cells.
Bodo Haas+7 more
doaj
Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue. [PDF]
Huang Z+14 more
europepmc +1 more source
The Regulator of G Protein Signaling 14 Knockout Mouse, a Model of Healthful Longevity Protects Against Obesity and Glucose Intolerance Through a Brown Adipose Tissue Mechanism. [PDF]
Vatner SF+3 more
europepmc +1 more source
A multi-tissue and -breed catalogue of chromatin conformations and their implications in gene regulation in pigs. [PDF]
Yin H+6 more
europepmc +1 more source
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang+7 more
wiley +1 more source
Synergistic Impact of Aerobic Exercise and Resveratrol on White Adipose Tissue Browning in Obese Rats: Mechanistic Exploration and Biological Insights. [PDF]
Hu Y, Wu Y, Wang C, Jin Q, Chen X.
europepmc +1 more source
Dynamics of adipose tissue turnover in human metabolic health and disease
Ursula A White, E. Ravussin
semanticscholar +1 more source
What's New? Sarcopenia is highly prevalent and associated with adverse outcomes in cancer survivors. However, evidence regarding the role of sarcopenia in the general population as a potential risk factor for cancer development is scarce. This prospective cohort study investigated the association of sarcopenia with the incidence of 19 cancers in a ...
Panagiotis Filis+8 more
wiley +1 more source
Puerarin affects adipose lipolysis and ameliorates obesity by gut microbiota. [PDF]
Li Z, Ye Y, Lai S, Bao J, Fu A.
europepmc +1 more source
Abstract Objective To identify potential biomarkers in patients with polycystic ovary syndrome (PCOS) and atherosclerosis, and to explore the common pathologic mechanisms between these two diseases in response to the increased risk of cardiovascular diseases in patients with PCOS.
Lirong Wang+7 more
wiley +1 more source