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Autophagy in White Adipose Tissue
2014Autophagy is a mechanism for intracellular degradation of cytoplasmic components including macromolecules and organelles. It has been shown to be involved in a large number of physiological and pathological processes. Studies have recently uncovered an important role of autophagy in the process of adipogenesis.
Shengkan ‘Victor’ Jin +2 more
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Explant Cultures of White Adipose Tissue
2008Obesity is characterized by increased adiposity of visceral and subcutaneous depots as well as other organs, including the vasculature. These fat depots secrete various hormone-like proteins implicated in metabolic homeostasis (e.g., adiponectin, resistin), the central control of appetite (e.g., leptin) and the increased production of cytokines.
Sébastien Thalmann +3 more
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Metabolism of White Adipose Tissue
2007Triacylglycerols (TAGs) stored in adipose tissue are by far the largest site of energy storage. Adipocytes continuously synthesize and break down these TAGs depending on the body energy status and its hormonal environment. They act as a “buffer” for plasma lipids and also for lipids stored in other tissues.
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White adipose tissue and cardiovascular disease
Best Practice & Research Clinical Endocrinology & Metabolism, 2005Adipocytes have recently been shown to secrete a variety of bioactive substances called 'adipocytokines', and have been recognized as endocrine cells. Tumour necrosis factor (TNF)-alphaalpha, plasminogen activator inhibitor-1 (PAI-1) and heparin-binding epidermal-growth-factor-like growth factor (HBEGF) are among these adipocytokines, and they ...
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Sandwiched White Adipose Tissue: A Microphysiological System of Primary Human Adipose Tissue
Tissue Engineering Part C: Methods, 2018White adipose tissue (WAT) is a critical organ in both health and disease. However, physiologically faithful tissue culture models of primary human WAT remain limited, at best. In this study we describe a novel WAT culture system in which primary human WAT is sandwiched between tissue-engineered sheets of adipose-derived stromal cells.
Maxwell Hunt +12 more
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Organ culture of rat white adipose tissue
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1972Abstract 1. 1. Intact rat epididymal fat pads were incubated for up to 6 days in Trowell's medium with 20% fetal calf serum. Fat pad DNA content fell by 30% after 6 days of incubation. The lipid content of the incubated fat pads increased by 11% after 3 days of incubation and then remained constant.
Jiří Frohlich +2 more
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In Vitro Culture of White Adipose Tissue
White adipose tissue (WAT) plays a crucial endocrine organ that regulates blood glucose and lipid levels, satiety, and inflammation. Before the described technique, primary white adipocytes could not be stably cultured in vitro. The lack of a reliable primary culture model impeded research in WAT metabolism and drug development.Jake J, Fontenot, Frank H, Lau
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Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Kimberly D Miller +2 more
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