Results 11 to 20 of about 233,820 (46)
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs
Science Translational Medicine, 2019 Tryptophan-derived metabolites from the gut microbiota control miR-181 expression in mouse white adipocytes to regulate metabolism and inflammation.
A. Virtue +22 more
semanticscholar +1 more source
Diabetes, 2017 Adipose-derived stem cells (ADSCs) play critical roles in controlling obesity-associated inflammation and metabolic disorders. Exosomes from ADSCs exert protective effects in several diseases, but their roles in obesity and related pathological ...
Hui Zhao +9 more
semanticscholar +1 more source
Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
BMC Biology, 2019 In mammals, cold exposure induces browning of white adipose tissue (WAT) and alters WAT gene expression and lipid metabolism to boost adaptive thermogenesis and maintain body temperature.
Ziye Xu +5 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2023 Overweight and obesity have become a world-wide problem. However, effective intervention approaches are limited. Brown adipose tissue, which helps maintain body temperature and contributes to thermogenesis, is dependent on uncoupling protein1.
Xiaomeng Liu +4 more
semanticscholar +1 more source
Fibroblast Growth Factor 21 and Browning of White Adipose Tissue
Frontiers in Physiology, 2019 Interest has been focused on differentiating anatomical, molecular, and physiological characteristics of the types of mammalian adipose tissues. White adipose tissue (WAT) and brown adipose tissue (BAT) are the two main forms of adipose tissue in humans.
R. Matteis +3 more
semanticscholar +1 more source
Deciphering White Adipose Tissue Heterogeneity
Biology, 2019 Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body.
Q. Luong, Jun Huang, Kevin Y. Lee
semanticscholar +1 more source
Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes
Journal of physiology and biochemistry, 2018 Mammalian adipose tissue is traditionally categorized into white and brown relating to their function and morphology: while white serves as an energy storage, brown adipose tissue acts as the heat generator maintaining the core body temperature. The most
A. Kaisanlahti, Tumo Glumoff
semanticscholar +1 more source
The Circadian Clock in White and Brown Adipose Tissue: Mechanistic, Endocrine, and Clinical Aspects.
Endocrine reviews, 2018 Obesity is a major risk factor for the development of illnesses, such as insulin resistance and hypertension, and has become a serious public health problem. Mammals have developed a circadian clock located in the hypothalamic suprachiasmatic nuclei (SCN)
O. Froy, M. Garaulet
semanticscholar +1 more source
PVAT and Its Relation to Brown, Beige, and White Adipose Tissue in Development and Function
Frontiers in Physiology, 2018 Adipose tissue is commonly categorized into three types with distinct functions, phenotypes, and anatomical localizations. White adipose tissue (WAT) is the major energy store; the largest depots of WAT are found in subcutaneous or intravisceral sites ...
S. Hildebrand, J. Stümer, A. Pfeifer
semanticscholar +1 more source
TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
Nature Communications, 2018 Remodelling of energy storing white fat into energy expending beige fat could be a promising strategy to reduce adiposity. Here, we show that the bile acid-responsive membrane receptor TGR5 mediates beiging of the subcutaneous white adipose tissue (scWAT)
L. Velázquez-Villegas +6 more
semanticscholar +1 more source