Results 21 to 30 of about 493,971 (354)
Effects of a Phosphodiesterase inhibitor on the Browning of Adipose Tissue in Mice
Biomedicines, 2022 Cilostazol is a selective inhibitor of phosphodiesterase type 3 (PDE3) that increases intracellular cyclic adenosine monophosphate (cAMP), which plays a critical role in the development of the beige phenotype and the activation of its thermogenic program
Da Hea Seo +6 more
doaj +1 more source
Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
Frontiers in Endocrinology, 2020 Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann +14 more
doaj +1 more source
The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least [PDF]
Endocrinology and Metabolism, 2023 The growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for
Juan Cai, Fenfen Wang, Mengle Shao
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Hysteresis of White Adipose Tissue
Open Journal of Endocrine and Metabolic Diseases, 2015 Objective: This study was performed to analyze the modifications within adipose tissue during calorie restriction and more specifically to state whether hysteresis occurs during fat mass reduction. Method: Rats male Wistar increased their body weight by 130 g under control conditions and were then submitted to a calorie restriction (CR) at 30% or 60 ...
Geloen, Alain +3 more
openaire +7 more sources
Frontiers in Cardiovascular Medicine, 2020 Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date several types of adipose tissue have been identified, namely white, brown, and beige, that reside in various specific anatomical locations throughout the body. The
Alan Chait, Laura J. den Hartigh
doaj +1 more source
Cold-Induced Changes in Gene Expression in Brown Adipose Tissue, White Adipose Tissue and Liver
PLoS ONE, 2013 Cold exposure imposes a metabolic challenge to mammals that is met by a coordinated response in different tissues to prevent hypothermia. This study reports a transcriptomic analysis in brown adipose tissue (BAT), white adipose (WAT) and liver of mice in
Andrew M. Shore +5 more
semanticscholar +1 more source
There and Back Again: Leptin Actions in White Adipose Tissue
International Journal of Molecular Sciences, 2020 Leptin is a hormone discovered almost 30 years ago with important implications in metabolism. It is primarily produced by white adipose tissue (WAT) in proportion to the amount of fat. The discovery of leptin was a turning point for two principle reasons:
N. Martínez-Sánchez
semanticscholar +1 more source
miR-34a-/- mice are susceptible to diet-induced obesity [PDF]
, 2016 Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H. +7 more
core +1 more source
Regulatory microRNAs in Brown, Brite and White Adipose Tissue
Cells, 2020 MicroRNAs (miRNAs) constitute a class of short noncoding RNAs which regulate gene expression by targeting messenger RNA, inducing translational repression and messenger RNA degradation.
S. Gharanei +6 more
semanticscholar +1 more source
Effect of Thyroid Hormones on Adipose Tissue Flexibility [PDF]
, 2023 The recruitment and activation of energy-consuming brown adipocytes is currently considered as potential therapeutic approach to combat obesity. Thyroid hormones (TH) significantly contribute to full thermogenic capacity of brown adipocytes.
Krause, Kerstin, Volke, Lisa
core +1 more source