Results 31 to 40 of about 348,557 (287)

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

open access: yesNature Communications, 2018
Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding   +12 more
doaj   +1 more source

Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer [PDF]

open access: yesPeerJ
Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood.
Xiufeng Zhang   +9 more
doaj   +2 more sources

Regulation of adipose tissue inflammation by interleukin 6

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Chronic low-grade inflammation is a key driver of metabolic syndrome. This inflammatory response is mediated by immune-cell infiltration and the expression of inflammatory cytokines.
M. Han   +6 more
semanticscholar   +1 more source

Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins

open access: yesNature Communications, 2022
White adipose tissue browning plays an important role in regulating whole-body energy homeostasis and metabolism. Here the authors show that the HMGN nucleosome binding proteins epigenetically promote white adipocyte differentiation and modulate the rate
Ravikanth Nanduri   +9 more
doaj   +1 more source

Latest Advancements on Combating Obesity by Targeting Human Brown/Beige Adipose Tissues

open access: yesFrontiers in Endocrinology, 2022
Obesity is defined as overaccumulation of white adipose tissue in the body, mainly under the skin (subcutaneous adiposity) or in the abdominal cavity (visceral adiposity).
Ruping Pan   +3 more
doaj   +1 more source

Effects of Different Fasting Modes Combined with Exercise Training on Browning of White Adipose Tissue in Mice [PDF]

open access: yesShipin Kexue
To investigate the effect of intermittent fasting (IF) combined with exercise on browning of white adipose tissue (WAT), we randomly divided male C57BL/6 mice aged 5–6 weeks into six groups: control (Con), exercise (Ex), alternate-day fasting (ADF ...
LI Yinhuan, WANG Xukai, SHI Jian, XU Linjing, ZHOU Lizi, LI Weiye, LIU Hui, LIU Chunhong
doaj   +1 more source

The adipose tissue: something more than a reservoir of energy

open access: yesGrasas y Aceites, 2009
Adipose tissue is a reservoir of energy and also an organ that contributes to the aesthetics and health of human body working as an endocrine tissue. White adipose tissue, which is formed by unilocular adipose cells, can modify organic homeostasis by ...
Alfonso Valenzuela B, Julio Sanhueza C
doaj   +1 more source

Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism

open access: yesFrontiers in Endocrinology, 2014
White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
doaj   +1 more source

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

open access: yesAdipocyte, 2021
Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng   +13 more
doaj   +1 more source

Spatial Metabolomics Reveals the Effects of Dietary Capsaicin Intervention on Interscapular Adipose Tissue Metabolome in Mice

open access: yesFoods
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy