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Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with Human
Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with ...
Teona Albertovna Shvangiradze
doaj +1 more source
Lipolysis and lipases in white adipose tissue – An update [PDF]
Lipolysis is defined as the sequential hydrolysis of triacylglycerol (TAG) stored in cell lipid droplets. For many years, it was believed that hormone-sensitive lipase (HSL) and monoacylglycerol lipase (MGL) were the main enzymes catalyzing lipolysis in the white adipose tissue.
Bolsoni-Lopes, Andressa+1 more
openaire +6 more sources
The immune and endocrine dysfunctions of white adipose tissue are a hallmark of metabolic disorders such as obesity and type 2 diabetes. In humans, white adipose tissue comprises distinct depots broadly distributed under the skin (hypodermis) and as ...
Leandra S. Baptista+4 more
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The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs
Tryptophan-derived metabolites from the gut microbiota control miR-181 expression in mouse white adipocytes to regulate metabolism and inflammation.
A. Virtue+22 more
semanticscholar +1 more source
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy expenditure, has been extensively studied as a potential avenue to combat obesity.
K. Ziqubu+7 more
semanticscholar +1 more source
White adipose tissue as a target for cadmium toxicity
Cadmium (Cd) is a widespread heavy metal known as a toxic environmental pollutant. Cd exposure is threatening due to its bioaccumulation trait in living systems that exceeds 35 years without a beneficial biological role. Acute exposure to high Cd doses was reported to impact adipose tissue (AT) function adversely.
Sarra Mohammed Attia+6 more
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Fibroblast Growth Factor 21 and Browning of White Adipose Tissue
Interest has been focused on differentiating anatomical, molecular, and physiological characteristics of the types of mammalian adipose tissues. White adipose tissue (WAT) and brown adipose tissue (BAT) are the two main forms of adipose tissue in humans.
R. Matteis+3 more
semanticscholar +1 more source
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source
Adipose tissue: colors, depots and functions
Obesity is a chronic disease characterized by excessive accumulation of adipose tissue. The prevalence of obesity and associated diseases has prompted researchers to expand the study of the biology of adipose tissue.
T. I. Romantsova
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Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source