Results 61 to 70 of about 244,844 (212)

Sex matters: The effects of biological sex on adipose tissue biology and energy metabolism

open access: yesRedox Biology, 2017
Adipose tissue is a complex and multi-faceted organ. It responds dynamically to internal and external stimuli, depending on the developmental stage and activity of the organism.
Teresa G. Valencak   +2 more
doaj   +1 more source

An integrated single cell and spatial transcriptomic map of human white adipose tissue

open access: yesNature Communications, 2023
Single-cell studies of human white adipose tissue (WAT) provide insights into the specialized cell types in the tissue. Here the authors combine publicly available and newly generated high-resolution and bulk transcriptomic results from multiple human ...
Lucas Massier   +27 more
doaj   +1 more source

HOXC10 suppresses browning of white adipose tissues [PDF]

open access: yesExperimental & Molecular Medicine, 2017
Given that increased thermogenesis in white adipose tissue, also known as browning, promotes energy expenditure, significant efforts have been invested to determine the molecular factors involved in this process. Here we show that HOXC10, a homeobox domain-containing transcription factor expressed in subcutaneous white adipose tissue, is a suppressor ...
Hwee Yim Angeline Tan   +9 more
openaire   +2 more sources

Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health [PDF]

open access: yes, 2016
Obesity constitutes a serious global health concern reaching pandemic prevalence rates. The existence of functional brown adipose tissue (BAT) in adult humans has provoked intense research interest in the role of this metabolically active tissue in whole-
Andrade, Cl��udia Marlise Balbinotti   +11 more
core   +1 more source

Adipose tissue: colors, depots and functions

open access: yesОжирение и метаболизм, 2021
Obesity is a chronic disease characterized by excessive accumulation of adipose tissue. The prevalence of obesity and associated diseases has prompted researchers to expand the study of the biology of adipose tissue.
T. I. Romantsova
doaj   +1 more source

Obesity, white adipose tissue and cancer

open access: yesThe FEBS Journal
White adipose tissue (WAT) is crucial for whole‐body energy homeostasis and plays an important role in metabolic and hormonal regulation. While healthy WAT undergoes controlled expansion and contraction to meet the body's requirements, dysfunctional WAT in conditions like obesity is characterized by excessive tissue expansion, alterations in lipid ...
Estel Solsona‐Vilarrasa   +1 more
openaire   +2 more sources

Dielectric properties measurements of brown and white adipose tissue in rats from 0.5 to 10 GHz [PDF]

open access: yes, 2016
Brown adipose tissue (BAT) plays an important role in whole body metabolism and with appropriate stimulus could potentially mediate weight gain and insulin sensitivity.
Colebeck, E.   +6 more
core   +2 more sources

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

open access: yes, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D.   +7 more
core   +2 more sources

Therapeutic targeting of white adipose tissue metabolic dysfunction in obesity: mechanisms and opportunities

open access: yesMedComm
White adipose tissue is not only a highly heterogeneous organ containing various cells, such as adipocytes, adipose stem and progenitor cells, and immune cells, but also an endocrine organ that is highly important for regulating metabolic and immune ...
Zi‐Han Yang   +7 more
doaj   +1 more source

Characteristics and mechanisms of subcutaneous and visceral adipose tissue aging

open access: yesChinese Journal of Plastic and Reconstructive Surgery
Aging is one of the most significant health challenges worldwide and is a primary cause of chronic diseases and physiological decline. Among the myriad changes that occur with aging, alterations in adipose tissue distribution and function have gained ...
Peng Xu, Yikai Wang, Kai Liu
doaj   +1 more source

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