Results 61 to 70 of about 348,557 (287)
The Circadian Clock in White and Brown Adipose Tissue: Mechanistic, Endocrine, and Clinical Aspects.
Endocrine reviews, 2018 Obesity is a major risk factor for the development of illnesses, such as insulin resistance and hypertension, and has become a serious public health problem. Mammals have developed a circadian clock located in the hypothalamic suprachiasmatic nuclei (SCN)
O. Froy, M. Garaulet
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng +5 more
wiley +1 more source
FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue
Molecular Metabolism, 2017 Objective: Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates metabolic homeostasis. Previous work has suggested that impairment of FGF21 signaling in adipose tissue may occur through downregulation of the obligate FGF21 co ...
Kathleen R. Markan +5 more
doaj
TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
Nature Communications, 2018 Remodelling of energy storing white fat into energy expending beige fat could be a promising strategy to reduce adiposity. Here, we show that the bile acid-responsive membrane receptor TGR5 mediates beiging of the subcutaneous white adipose tissue (scWAT)
L. Velázquez-Villegas +6 more
semanticscholar +1 more source
Metabolic control by AMPK in white adipose tissue
Trends in Endocrinology & Metabolism, 2023 White adipose tissue (WAT) plays an important role in the integration of whole-body metabolism by storing fat and mobilizing triacylglycerol when needed. The released free fatty acids can then be oxidized by other tissues to provide ATP. AMP-activated protein kinase (AMPK) is a key regulator of metabolic pathways, and can be targeted by a new ...
Olga Göransson +2 more
openaire +3 more sources
Advanced Materials, EarlyView.This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang +3 more
wiley +1 more source
Adipose-Derived Stem Cells: Isolation, Characterization, and Differentiation Potential
Cell Transplantation, 2013 In mammals, the two main types of adipose tissues, white and brown adipose tissues, exert different physiological functions. White adipose tissue (WAT) is for storing energy, while brown adipose tissue (BAT) is for energy consumption.
Shyh-Jer Huang +9 more
doaj +1 more source
The Impact of the Adipose Organ Plasticity on Inflammation and Cancer Progression
Cells, 2019 Obesity is characterized by chronic and low-grade systemic inflammation, an increase of adipose tissue, hypertrophy, and hyperplasia of adipocytes.
Luís Henrique Corrêa +2 more
doaj +1 more source
EGCG Reduces Obesity and White Adipose Tissue Gain Partly Through AMPK Activation in Mice
Frontiers in Pharmacology, 2018 (-)-Epigallocatechin-3-gallate (EGCG), which is the most abundant catechin in green tea, has many potential health benefits, including decreased weight gain and/or adipose tissue weight. Suggested mechanisms for body weight reduction by EGCG include: (1)
Fang Li +8 more
semanticscholar +1 more source