Results 111 to 120 of about 4,418,865 (434)
Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]
, 2018 Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G. +13 more
core +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
RPB4 and pathogenesis of diabetes [PDF]
, 2007 Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh +1 more
core +1 more source
Ortho-positronium Lifetime For Soft-tissue Classification [PDF]
Scientific Reports 14.1 (2024): 21155The objective of this work is to showcase the ortho-positronium lifetime as a probe for soft-tissue characterization. We employed positron annihilation lifetime spectroscopy to experimentally measure the three components of the positron annihilation lifetime para-positronium (p-Ps), positron, and ortho-positronium (o-Ps) for three types of porcine, non-
arxiv +1 more source
Contribution of adipogenesis to healthy adipose tissue expansion in obesity.
Journal of Clinical Investigation, 2019 The manner in which white adipose tissue (WAT) expands and remodels directly impacts the risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT is associated with increased risk for insulin resistance, whereas ...
Lavanya Vishvanath, Rana K. Gupta
semanticscholar +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Functional brown adipose tissue in healthy adults.
New England Journal of Medicine, 2009 Using positron-emission tomography (PET), we found that cold-induced glucose uptake was increased by a factor of 15 in paracervical and supraclavicular adipose tissue in five healthy subjects.
K. Virtanen +10 more
semanticscholar +1 more source
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose Palliative radiotherapy comprises a significant portion of the radiation treatment workload. Volumetric‐modulated arc therapy (VMAT) improves dose conformity and, in conjunction with flattening filter free (FFF) delivery, can decrease treatment times, both of which are desirable in a population with a high probability of retreatment ...
Madeleine L. Van de Kleut +2 more
wiley +1 more source
, 2019 In this issue of JEM, Rana et al. (https://doi.org/10.1084/jem.20190689) report that adipose tissue multipotent stromal cells (MSCs) provide multifaceted support for adipose tissue-resident ILC2s through contact-mediated proliferation and IL-33-mediated ...
Locksley, Richard M +1 more
core +1 more source
Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells. [PDF]
, 2014 The increased incidence of obesity and metabolic disease underscores the importance of elucidating the biology of adipose tissue development. The recent discovery of cell surface markers for prospective identification of adipose precursor cells (APCs) in
Costa, Maria José +3 more
core +2 more sources