Results 131 to 140 of about 4,454,348 (409)

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Ectopic Adipose Tissue Storage in the Left and the Right Renal Sinus is Asymmetric and Associated With Serum Kidney Injury Molecule-1 and Fibroblast Growth Factor-21 Levels Increase

EBioMedicine, 2016
Objective: A potential mechanism by which obesity could promote hypertension and kidney diseases is through accumulation of adipose tissue in the renal sinus (RS).
Gita Krievina, MSc, Peteris Tretjakovs, Biol PhD, Ilze Skuja, MD, Vija Silina, MD, Laura Keisa, MD, Daiga Krievina, MSc, Guntis Bahs, MD PhD   +6 more
doaj   +1 more source

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism [PDF]

, 2012
The prevalence of obesity and type 2-diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a major pathogenic factor.
Abumrad, Nada A., Blüher, Matthias, Herman, Mark Andrew, Kahn, Barbara, Klein, Samuel, Peroni, Odile Daniele, Schön, Michael R., Villoria, Jorge   +7 more
core   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Molecular mechanism underlying nutritional control of inflammatory responses

Journal of Physical Fitness and Sports Medicine, 2017
Storage of excessive energy as triglycerides is a fundamental function of adipose tissue. Adipose tissue also secrets a number of hormones termed “adipocytokines” or “adipokines” in response to the systemic nutritional status, thereby constituting a ...
Miyako Tanaka, Takayoshi Suganami
doaj   +1 more source

Noggin depletion in adipocytes promotes obesity in mice. [PDF]

, 2019
ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M, Boström, Kristina I, Fogelman, Alan M, Guo, Yina, Jumabay, Medet, Lusis, Aldons J, Rajbhandari, Prashant, Reue, Karen, Sallam, Tamer, Tontonoz, Peter, Vergnes, Laurent, Wu, Xiuju, Yao, Jiayi, Yao, Yucheng, Zhang, Li   +14 more
core   +1 more source

Association of 11β-hydroxysteroid dehydrogenase type I expression and activity with estrogen receptor β in adipose tissue from postmenopausal women [PDF]

, 2012
OBJECTIVE: 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) regenerates active cortisol from inert cortisone in adipose tissue. Elevated adipose tissue 11βHSD1 activity is observed in obese humans and rodents where it is linked to obesity and its ...
Cecilia Mattsson, Dieudonne, Heine, Horenburg, Hughes, Ingegerd Söderström, Jonathan R. Seckl, Kerry J. McInnes, Kotryna Šimonytė, McInnes, Sierens, Sorensen, Therése C. Andersson, Tommy Olsson, Walker   +14 more
core   +1 more source

A single-cell atlas of human and mouse white adipose tissue

Nature, 2021
Margo P. Emont, Christopher Jacobs, A. Essene, Deepti Pant, Danielle E. Tenen, G. Colleluori, A. Di Vincenzo, A. M. Jørgensen, Hesam T. Dashti, Adam Štefek, Elizabeth McGonagle, S. Strobel, Samantha Laber, Saaket Agrawal, Gregory P. Westcott, Amrita Kar, Molly L. Veregge, Anton Gulko, Harini Srinivasan, Zachary B. Kramer, Eleanna De Filippis, Erin Merkel, J. Ducie, Christopher G. Boyd, W. Gourash, A. Courcoulas, Samuel J. Lin, Bernard T. Lee, D. Morris, Adam M. Tobias, A. Khera, M. Claussnitzer, T. Pers, A. Giordano, Orr Ashenberg, A. Regev, Linus T. Tsai, E. Rosen   +37 more
semanticscholar   +1 more source

The Role of Adipose Tissue Mitochondria: Regulation of Mitochondrial Function for the Treatment of Metabolic Diseases

International Journal of Molecular Sciences, 2019
Mitochondria play a key role in maintaining energy homeostasis in metabolic tissues, including adipose tissues. The two main types of adipose tissues are the white adipose tissue (WAT) and the brown adipose tissue (BAT).
Jae Ho Lee, Anna Park, Kyoung-Jin Oh, Sang Chul Lee, W. Kim, K. Bae   +5 more
semanticscholar   +1 more source

High‐Throughput Encapsulation of Stem Cells: Characterizing Dynamic Culture Variability With a Millifluidic Approach

Advanced Healthcare Materials, EarlyView.
A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte, Marta Serra, Simon Kahlenberg, Guruprakash Subbiahdoss, Erik Reimhult, Dominik Egger, Cornelia Kasper   +6 more
wiley   +1 more source