Results 71 to 80 of about 691,764 (342)

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

In preeclampsia, maternal third trimester subcutaneous adipocyte lipolysis is more resistant to suppression by insulin than in healthy pregnancy [PDF]

open access: yes, 2014
Obesity increases preeclampsia risk, and maternal dyslipidemia may result from exaggerated adipocyte lipolysis. We compared adipocyte function in preeclampsia with healthy pregnancy to establish whether there is increased lipolysis.
Forrest, Rachel.   +5 more
core   +1 more source

Orbital adipose tissue

open access: yesОфтальмохирургия, 2016
We summarized the results of Russian and foreign researches elucidating embryogenesis, topography and anatomy of different orbital fat pads. It is interesting that adipose tissue from different surgical adipose spaces do not stem from the same germ ...
S. A. Borzenok   +3 more
doaj   +1 more source

Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice

open access: yesNature Communications, 2023
Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han   +15 more
doaj   +1 more source

Adipose tissue estimation of foraging and nesting green turtles Chelonia mydas using bioelectrical impedance analysis

open access: yesEndangered Species Research, 2023
Adipose tissue is the main energy store in sea turtles and fluctuates in response to dietary conditions and external stressors. Monitoring programmes commonly use body condition indices (BCIs) to infer the nutritional and health status of sea turtle ...
S Kophamel   +6 more
doaj   +1 more source

Offspring subcutaneous adipose markers are sensitive to the timing of maternal gestational weight gain [PDF]

open access: yes, 2015
peer-reviewedBackground Excessive maternal weight gain during pregnancy impacts on offspring health. This study focused on the timing of maternal gestational weight gain, using a porcine model with mothers of normal pre-pregnancy weight.
Berry, Donagh   +7 more
core   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

open access: yesArthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai   +12 more
wiley   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

open access: yesAdvanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau   +8 more
wiley   +1 more source

Development and validation of a rapid and robust method to determine visceral adipose tissue volume using computed tomography images. [PDF]

open access: yesPLoS ONE, 2017
Visceral adiposity is a risk factor for many chronic diseases. Existing methods to quantify visceral adipose tissue volume using computed tomographic (CT) images often use a single slice, are manual, and are time consuming, making them impractical for ...
Aaroh M Parikh   +6 more
doaj   +1 more source

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